March 1993 in “Neuroscience letters” Biotin is important for metabolism, with specific daily intake recommendations, and deficiency can cause health problems.
April 2021 in “Medical Science and Discovery” Early hair loss in men may signal broader health issues similar to PCOS in women.
22 citations
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September 2011 in “Journal of Investigative Dermatology” TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
January 2025 in “Japanese Journal of Gastroenterology and Hepatology” NAFLD is common in women with PCOS and may signal metabolic syndrome.
May 2020 in “Current developments in nutrition” Vitamin A affects the resting phase of hair growth, with both low and high levels increasing the number of hair follicles in this phase.
144 citations
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August 2019 in “Cells” The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
7 citations
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July 2025 in “Nature Communications” Piezo1 helps skin grow by managing metabolism and inflammation.
May 2007 in “Proceedings of the National Academy of Sciences of the United States of America” Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
25 citations
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September 2020 in “Molecules” Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
October 2025 in “Cell Proliferation” IL10_ApoEVs improve skin healing and reduce scarring.
14 citations
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October 2020 in “Journal of ethnopharmacology” Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.
2 citations
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January 2025 in “动物学研究” YAP1 helps fat cell formation by influencing the Hippo pathway.
1 citations
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March 2025 in “Journal of Investigative Dermatology” Metabolic issues may trigger lymphocytic cicatricial alopecia, and treatments targeting these issues could help.
IL6 is linked to higher risk of heart disease in people with a certain mouth condition.
February 2026 in “Biomedicine & Pharmacotherapy” MLPH helps hair grow by activating IGF-1 signaling in hair cells.
February 2025 in “Scientific Reports” Lipids may help treat hair loss by promoting hair growth.
November 2024 in “Research Square (Research Square)” Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” TLR2, a component in hair follicle stem cells, is crucial for healthy hair growth and regeneration, and its decrease can lead to hair loss.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
3 citations
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January 2025 in “Burns & Trauma” Glucose metabolism is crucial for wound healing but can delay healing in chronic wounds due to increased stress and inflammation.
PPARβ/δ helps yaks adapt to high altitudes by regulating lipid metabolism in their coats.
January 2019 in “Social Science Research Network” Hair follicle stem cells prevent melanocyte stem cells from differentiating by controlling retinoic acid levels.
20 citations
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September 2005 in “Clinics in Dermatology” Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.
August 2023 in “Frontiers in Oncology” New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.
January 2024 in “Wiadomości Lekarskie” Ancient immune and signaling pathways still regulate blood cell development.
14 citations
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May 2020 in “Biomolecules & Therapeutics” Vanillic acid from wheat bran may promote hair growth by activating certain cell pathways and reversing hormone-related hair loss.
130 citations
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March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
5 citations
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February 2025 in “Frontiers in Immunology” Lactate is vital for skin health, influencing metabolism, the skin barrier, immune responses, and has therapeutic potential for skin disorders.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.