25 citations
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January 2004 in “The International Journal of Developmental Biology” Research on skin disorders in humans and mice has improved understanding of hair and skin development.
47 citations
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August 2016 in “American Journal Of Pathology” Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
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April 2015 in “Journal of Investigative Dermatology” GasderminA3 is important for normal hair cycle transitions by controlling Wnt signaling.
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January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
April 2023 in “Dermatology practical & conceptual” Lenalidomide helps hair follicle stem cells turn into melanocytes, which may improve repigmentation in vitiligo.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
89 citations
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May 2005 in “Stem Cells” Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.
6 citations
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April 2010 in “The American Journal of Surgical Pathology” Trichoblastoma in the breast can be mistaken for cancer, so expert review is crucial to avoid misdiagnosis.
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February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
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July 1997 in “British Journal of Dermatology” The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
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June 2018 in “Journal of Dental Research” Msx2 is essential for proper enamel formation by preventing abnormal cell transformation.
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February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
December 2025 in “Italian Journal of Anatomy and Embryology” Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
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January 2024 in “Science Advances” Touch dome keratinocytes in adult skin have traits of different skin cell types.
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March 1995 in “PLANT PHYSIOLOGY” The differentiation stage of root epidermal cells is crucial for root hair depolarization in Medicago sativa when exposed to specific Nod factors.
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March 2014 in “Journal of Innovative Optical Health Sciences” Hair structure worsens as tumors grow in mice.
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May 2019 in “Stem cell reviews” Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
67 citations
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November 2019 in “Nature Communications” Oncogenic melanocyte stem cells can develop into melanoma similar to human cases.
April 2016 in “Journal of Investigative Dermatology” Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.
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December 2008 in “Molecular Carcinogenesis” The PML protein helps prevent skin cancer in mice.
August 2021 in “Research Square (Research Square)” StemMACS media is better for growing therapeutic stem cells.
August 2021 in “Journal of Investigative Dermatology” Adjusting polyamine levels could help treat skin disorders like psoriasis and skin cancer.
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April 2000 in “Archives of Pathology & Laboratory Medicine” 13 citations
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November 2003 in “Humana Press eBooks” ES cells can be turned into hair follicle cells in a lab setting.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” Estrogen speeds up hair follicle cell death, causing early hair growth cycle changes, but only if a specific receptor is present.
Retinoic acid can change skin development, like turning scales into feathers or forming glands.
January 2008 in “Yearbook of Dermatology and Dermatologic Surgery” Scientists can make stem cells that can turn into any cell type.
February 2026 in “Human Cell” MSC-CM can boost skin cell growth and movement, aiding skin repair.
May 2023 in “Stem cell research & therapy” New method efficiently isolates hair growth cells from newborn mouse skin.