January 2023 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” Combining metformin with myo-inositol is more effective for treating PCOS than metformin alone.
May 2026 in “Quality in Sport” Berberine may help improve insulin sensitivity, hormone balance, and reproductive function in women with PCOS.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
238 citations
,
February 2007 in “Journal of Neuroscience” Ovarian and stress hormones can change GABA A receptors through neurosteroids.
January 2020 in “ScholarWorks (Central Washington University)” NAG-1 may help prevent some metabolic issues related to PCOS.
5 citations
,
July 2020 in “PubMed” Both oral contraceptives reduced hirsutism in PCOS patients, but adding metformin showed no extra benefit.
1 citations
,
April 2024 in “Anais Brasileiros de Dermatologia” 9 citations
,
June 2017 in “Pharmacological Reports” ATP-sensitive potassium channels play a role in chloroquine-induced itch in mice.
26 citations
,
September 2024 in “Perspectives in Clinical Research” Drug repurposing offers faster, cheaper drug development but faces challenges like safety, ethics, and funding.
9 citations
,
October 2012 in “Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology” Stopping the drug olanzapine can reverse hair loss caused by it.
September 2021 in “Assay and drug development technologies” Drug repurposing shows promise for treating many medical conditions.
2 citations
,
September 2013 in “Journal of the Turkish-German Gynecological Association” Drugs for PCOS can affect metabolism, so understanding their effects is important for managing health risks.
March 2016 in “National Repository of Dissertations in Serbia” Dutasteride is more cost-effective than finasteride for treating benign prostatic hyperplasia in Montenegro.
5 citations
,
October 2014 in “Gynecological Endocrinology” Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.
7 citations
,
March 2019 in “Journal of The European Academy of Dermatology and Venereology” A man developed a skin reaction from metronidazole, which improved after stopping the drug and starting steroids.
36 citations
,
May 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.
5 citations
,
January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil is an effective and safe treatment for hair loss.
52 citations
,
October 2004 in “Veterinary dermatology” Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.
40 citations
,
December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
Low-dose oral minoxidil is generally safe for treating hair loss, with mostly mild side effects.
October 2025 in “Minerva Obstetrics and Gynecology” Choosing the right estroprogestin is crucial for effectively managing PCOS symptoms.
2 citations
,
February 2022 in “Frontiers in Endocrinology” Antiandrogenic pretreatment for women with PCOS does not improve fertility outcomes and delays pregnancy.
5 citations
,
December 2014 in “Medicine and Pharmacy Reports” Ciproterone acetate improves hair regrowth and acne in most female patients.
Suppressing ODC activity reduces tumor growth in hair follicles.
17 citations
,
October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
6 citations
,
July 2016 in “Doklady Biochemistry and Biophysics” GD-23 reduces anxiety by relying on neurosteroid production.
October 2025 in “Open Repository of the University of Porto (University of Porto)” Dutasteride is more effective than finasteride for hair growth, and sublingual apomorphine quickly improves Parkinson's symptoms.
5 citations
,
December 2021 in “Skin Pharmacology and Physiology” Metformin helps lab-grown skin and hair cells work better to create hair.
Minoxidil can cause hair growth as a side effect.
January 2021 in “Systematic Reviews in Pharmacy” Melatonin and minoxidil together may improve hair growth when applied to the skin.