research Keratin network modifications lead to the mechanical stiffening of the hair follicle fiber
Changes in keratin make hair follicles stiffer.
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research Ozone and procaine increase secretion of platelet-derived factors in platelet-rich plasma
Ozone and procaine boost the release of healing factors in platelet-rich plasma.
research Ultrasound-activated particles as CRISPR/Cas9 delivery system for androgenic alopecia therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation
Increasing Smurf2 hinders hair follicle stem cell differentiation and wound healing.
research Scratching the surface of skin development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research Regulation of somatic cell reprogramming through inducible mir-302 expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
research Types I and II Keratin Intermediate Filaments
Keratins are crucial for cell structure, growth, and disease risk.
research Building Epithelial Tissues from Skin Stem Cells
Skin stem cells help maintain skin health, grow hair, and heal wounds.
research Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth
Dermal Papilla cells are a promising tool for evaluating hair growth treatments.
research Mechanical forces in skin disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Perspectives of Kennedy's disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis
Hair loss in balding individuals is linked to changes in specific hair growth-related genes.
research Recently Identified Forms of Epidermolysis Bullosa
Three new types of a skin blistering disease were found, caused by specific gene mutations.
research How Does pH Fit in with Oscillating Polar Growth?
pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.
research Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs
Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
research Epidermal Polarity Genes in Health and Disease
Disruptions in epidermal polarity genes can lead to skin diseases.
research Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate
Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance
The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
research Comparative study on seasonal hair follicle cycling by analysis of the transcriptomes from cashmere and milk goats
Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.
research Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dots
The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.
research Identification of key genes induced by platelet-rich plasma in human dermal papilla cells using bioinformatics methods
Platelet-rich plasma may help hair follicle cells grow by affecting certain genes and pathways.
research Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice
Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.
research Epigallocatechin-3-gallate inhibits paclitaxel-induced apoptosis through the alteration of microRNA expression in human dermal papilla cells
Green tea extract helps prevent cell death and supports cell survival in hair cells exposed to a chemotherapy drug.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research A single-cell transcriptomic atlas elucidates the hair cycle and apoptosis mechanisms in goat hair follicles
The study maps goat hair follicle cells, revealing key genes and pathways involved in hair growth and cell death.
research Translational research in the generation of therapeutic medicine for wound healing: a review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.