June 2020 in “Journal of Investigative Dermatology” Scientists successfully grew mini hair follicles using human skin cells, which could help treat baldness.
April 2018 in “D-Scholarship@Pitt (University of Pittsburgh)” Keratin-75 is secreted by ameloblasts in a unique way without a signal peptide.
April 2018 in “Journal of Investigative Dermatology” Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
April 2015 in “Andrology” HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.
Laser hair removal may cause skin changes that prevent hair regrowth.
Type II spiral ganglion neurites avoid high concentrations of laminin and fibronectin.
May 2009 in “Medical and surgical dermatology/Medical & surgical dermatology” Hair and nail conditions can stabilize or improve over time, and new treatments show promise.
130 citations
,
September 2018 in “Cell Reports” Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
87 citations
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July 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
60 citations
,
July 2020 in “ACS Nano” Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
48 citations
,
April 2024 in “Nature Communications” The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
47 citations
,
December 2019 in “Biomaterials” Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
47 citations
,
September 2015 in “Journal of Drug Delivery Science and Technology” Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.
47 citations
,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
46 citations
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January 2020 in “Theranostics” Injecting a special gel with human protein particles can help hair grow.
41 citations
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November 2024 in “Molecular Biomedicine” Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
36 citations
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February 2018 in “British Journal of Dermatology” Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.
27 citations
,
March 2022 in “Forensic Toxicology” Micro-segmental hair analysis helps detect drug use patterns and estimate drug consumption days.
27 citations
,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
26 citations
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June 2020 in “Polymers” Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
24 citations
,
June 2021 in “Agronomy” Protein hydrolysates applied to roots or leaves differently improved lettuce yield and quality, with the best results seen in specific combined treatments for each type.
24 citations
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October 2019 in “Biomaterials Research” Minoxidil in HA-PLGA nanoparticles effectively treats alopecia through skin delivery.
23 citations
,
January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
22 citations
,
August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
22 citations
,
November 2005 in “BMC Cancer” Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.
20 citations
,
January 2015 in “Polish Journal of Pathology” Reflectance confocal microscopy is a useful, non-invasive tool for diagnosing some skin diseases, with potential for future improvements.
19 citations
,
January 2009 in “International review of cell and molecular biology” Hair's strength and flexibility come from its protein structure and molecular interactions.
18 citations
,
February 2023 in “PLoS ONE” A new triple drug system using nanoparticles effectively targets breast tumors in 3D models.