research Probing neuronal functions with precise and targeted laser ablation in the living cortex
The laser system helps study brain cell functions by precisely removing specific cells and observing changes.
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research Machine Learning-Driven Optimization of Therapeutic Substance Composition for High-Hardness, Fast-Dissolving Microneedles for Androgenetic Alopecia Treatment.
Machine learning optimized microneedles for hair loss treatment showed better hair regrowth than minoxidil without safety risks.
research Spatiotemporal immunomodulation by engineered hair follicle stem cell-derived nanovesicles enables scarless regeneration of infected wounds
Engineered nanovesicles from hair follicle stem cells enable scarless healing of infected wounds.
research Engineered TGF-β-Enriched Exosomes Delivered by Dissolving Microneedles for Androgenetic Alopecia Therapy
research A molecular systems architecture of the mesenchymal stromal cell microenvironment
A systems biology approach helps improve mesenchymal stromal cell therapies by mapping interactions and identifying treatment targets.
research In vitro 3D organotypic hair follicle-model for high-throughput substance testing
The 5050 MHA42MCS45 hydrogel blend is suitable for repairing load-bearing soft tissues.
research A Fibrous Hybrid Patch Couples Cell-Derived Matrix and Poly(l -lactide-co-caprolactone) for Endothelial Cells Delivery and Skin Wound Repair
The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
research Microencapsulation of Poorly Water-soluble Finasteride in Polyvinyl Alcohol/chitosan Microspheres as a Long-term Sustained Release System for Potential Embolization Applications
research Remote loading of minoxidil in nano-reservoirs leads to polymorphism and controlled release
research Androgenetic alopecia and microneedling: Every needling is not microneedling
Microneedling improves hair growth in androgenetic alopecia when combined with minoxidil.
research Biomedical Applications of Layer‐by‐Layer Self‐Assembly for Cell Encapsulation: Current Status and Future Perspectives
Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
research Back cover
A new treatment using special microneedles and a nitric oxide-releasing drug could improve hair growth and be more convenient for people with hair loss.
research A Mosaic Hotspot PLCD1 Variant, Detectable in Blood‐Derived DNA , Associated With Nevus Trichilemmocysticus
A rare genetic variant linked to skin cysts was found in blood DNA, suggesting its role in cyst formation.
research Unique Circulating MicroRNA Signatures Distinguish Severe Alopecia Areata from Other Inflammatory Skin Diseases
Unique microRNA patterns can help diagnose and treat severe alopecia areata.
research Reflectance confocal microscopy can differentiate dermoscopic white dots of the scalp between sweat gland ducts or follicular infundibulum
Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.
research Author response: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
ERK activation spreads between cells, influencing cell division and wound healing.
research Microneedling as a monotherapy in treatment of male androgenetic alopecia
research Clinical efficacy of polyglutamate via microneedle delivery: a novel non-invasive therapy for androgenetic alopecia
Microneedle-delivered polyglutamate effectively and safely improves hair growth in androgenetic alopecia.
research Interdisciplinarity traditional Chinese medicine microneedles in skin disease treatment: Recent advances and challenges
Combining traditional Chinese medicine with microneedles shows promise for effectively treating skin diseases with fewer side effects.
research Watching stem cells at work with a flexible multiphoton tomograph
A new imaging technique can observe stem cells in living mice without harming them.
research Microvascular Remodeling Strategy for Skin Rejuvenation through Microenvironmental Reprogramming and Appendage Restoration
research 0957 When AI helps developing an innovative anti-aging biofunctional
The new anti-aging ingredient improves skin hydration, elasticity, and reduces wrinkles.
research Dissolving microneedles for alopecia treatment
Dissolving microneedles show promise for treating hair loss but need more research for practical use.
research Three-dimensional microanatomy of mechanoreceptors and their possible mechanism of sensory transduction.
Mechanoreceptors convert physical touch into electrical signals through specialized nerve structures.
research Characteristics and Hair Growth Efficacy of Water Dissolving Micro-needles Containing Minoxidil Regarding Length of Micro-needles
Micro-needles with minoxidil may help hair growth.
research Use of confocal microscopy for nanoparticle drug delivery through skin
Confocal microscopy is useful for studying how nanoparticles interact with skin.
research Shh pathway in wounds in non-diabetic Shh-Cre-eGFP/Ptch1-LacZ mice treated with MAA beads
MAA beads improved wound healing in male mice by activating the Shh pathway, but not in females.
research Data Sheet 1_SHP099-containing multi-targeting hydrogel promotes rapid skin reconstruction through modulating a variety of cells.zip
Gel-SHP hydrogel speeds up wound healing by helping different cells work better.
research Life Sciences Discovery and Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research MicroRNA-181a Targets GNAI2 and Affects the Proliferation and Induction Ability of Dermal Papilla Cells: The Potential Involvement of the Wnt/β-Catenin Signaling Pathway
MicroRNA-181a slows sheep hair growth by targeting GNAI2 and affecting a key growth pathway.