65 citations
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April 2021 in “Natural Products and Bioprospecting” Dendrobium plants have compounds useful for treating skin issues and developing new drugs and cosmetics.
62 citations
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October 2016 in “Dermatologic Therapy” PRP more effective than minoxidil 5% for treating alopecia areata.
60 citations
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January 1989 in “Toxicologic Pathology” Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.
58 citations
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July 1986 in “Journal of The American Academy of Dermatology” Lowest effective minoxidil concentration is 1%, but 2% works better for male pattern baldness.
57 citations
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August 2003 in “British Journal of Dermatology” Minoxidil and pyrithione zinc combo most effectively increases hair density.
54 citations
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March 1987 in “Journal of The American Academy of Dermatology” 3% topical minoxidil effectively treats extensive alopecia areata with few side effects.
51 citations
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March 1987 in “Journal of The American Academy of Dermatology” Minoxidil keeps most hair growth from first year and twice-daily use is better with few side effects.
50 citations
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September 1975 in “American Heart Journal” Minoxidil effectively controls blood pressure in severe cases, but may cause fluid retention and edema.
46 citations
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September 2014 in “Steroids” Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.
44 citations
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October 1989 in “International Journal of Pharmaceutics” Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.
41 citations
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March 1987 in “Journal of The American Academy of Dermatology” Topical minoxidil effectively treats male pattern baldness and prevents hair loss.
39 citations
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February 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.
38 citations
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June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
36 citations
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November 2018 in “BMC plant biology” ROXY proteins help plants respond to nitrate shortage by affecting nutrient sensing and growth.
35 citations
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July 1981 in “Clinical Pharmacology & Therapeutics” Minoxidil can cause dangerous fluid buildup around the heart.
35 citations
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August 1980 in “Circulation” Minoxidil may cause heart issues in animals and humans.
34 citations
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July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
34 citations
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September 1985 in “Contact Dermatitis” Minoxidil can cause skin irritation like eczema and rash in some users.
33 citations
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October 2013 in “Journal of The American Academy of Dermatology” Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.
33 citations
,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
32 citations
,
January 2019 in “American Journal of Clinical Dermatology” Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.
31 citations
,
August 1975 in “Journal of Pharmaceutical Sciences” Minoxidil metabolizes similarly in monkeys and humans, but differently in dogs and rats.
28 citations
,
September 2019 in “International Journal of Nanomedicine” Minoxidil nanoparticles can potentially be a more effective treatment for hair growth than current treatments.
28 citations
,
March 2017 in “Scientific Reports” Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
27 citations
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September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
26 citations
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January 1978 in “Nephron” Minoxidil lowers blood pressure effectively but may cause side effects.
26 citations
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October 1978 in “JAMA” Minoxidil helps treat severe high blood pressure.
25 citations
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June 2018 in “Clinical and Experimental Dermatology” Combined microneedling and minoxidil improves hair growth more than minoxidil alone.
24 citations
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September 2020 in “Dermatology and therapy” Oral minoxidil 5 mg daily increases hair growth safely in men with hair loss, with minor side effects.
24 citations
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May 2013 in “Drug Design Development and Therapy” Multimodal minoxidil microemulsion is more effective in treating hair loss than minoxidil alone.