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,
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,
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,
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,
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,
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31 citations
,
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,
December 2021 in “Biomedicines” Exosomes from different stem cell sources affect immune cells and brain cell growth differently.
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,
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,
February 2023 in “Frontiers in Cell and Developmental Biology” WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
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,
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,
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,
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,
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,
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,
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22 citations
,
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,
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,
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21 citations
,
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,
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,
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,
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21 citations
,
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20 citations
,
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19 citations
,
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19 citations
,
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19 citations
,
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18 citations
,
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,
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,
December 2021 in “Journal of Nanobiotechnology” The nanofibers effectively treated infected diabetic wounds by killing bacteria and aiding wound healing without toxicity.