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,
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Chirality influences the structure, strength, and biological uses of peptide-based hydrogels.
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,
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287 citations
,
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266 citations
,
January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
215 citations
,
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186 citations
,
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173 citations
,
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166 citations
,
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140 citations
,
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105 citations
,
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99 citations
,
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98 citations
,
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97 citations
,
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85 citations
,
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84 citations
,
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81 citations
,
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75 citations
,
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70 citations
,
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68 citations
,
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60 citations
,
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57 citations
,
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52 citations
,
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50 citations
,
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48 citations
,
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48 citations
,
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46 citations
,
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45 citations
,
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45 citations
,
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