171 citations
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October 1990 in “Alcoholism/Alcoholism, clinical and experimental research” The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.
66 citations
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October 1984 in “Annual Review of Microbiology” Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.
57 citations
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January 1986 in “The Prostate” The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
52 citations
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June 1981 in “International Journal of Dermatology” Oral retinoids are effective for severe skin conditions but require careful use due to side effects.
3 citations
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March 2015 in “Journal of the European Academy of Dermatology and Venereology” Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.
18 citations
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June 1988 in “Culture, medicine and psychiatry” The perception of excessive hair growth in women as abnormal is more influenced by cultural norms than by medical reasons.
421 citations
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April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
77 citations
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July 2020 in “Cell” Muscles and nerves that cause goosebumps also help control hair growth.
67 citations
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February 2020 in “Journal of Ginseng Research” Korean Red Ginseng has beneficial components that help with stress, immunity, fatigue, memory, blood flow, and disease protection.
20 citations
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January 2013 in “Cell & Bioscience” Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.
14 citations
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December 2016 in “PloS one” Keratin 26 affects cashmere goat hair growth and is influenced by various treatments.
6 citations
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October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
1 citations
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April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene therapy in mice increased lifespan and improved health without causing cancer.
Biotin boosts wool growth and follicle health in sheep.
17 citations
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July 2024 in “Frontiers in Oncology” New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
11 citations
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December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
87 citations
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September 2019 in “Nature Communications” SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
145 citations
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May 2008 in “Cancer Science” Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.
31 citations
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April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
26 citations
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December 2020 in “Nature metabolism” Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.
January 2023 in “International journal of biological sciences” COX2 and ATP synthase control the size of hedgehog spines.
December 1991 in “Annals of the New York Academy of Sciences” Keratin proteins are crucial for hair structure and strength.
27 citations
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January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
70 citations
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July 2005 in “Journal of Ethnopharmacology” Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.
August 1986 in “Journal of The American Academy of Dermatology” Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.
124 citations
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September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
112 citations
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May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
103 citations
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October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
12 citations
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June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.