research IL-17a induces age-related olfactory dysfunction by impairing regeneration and promoting respiratory metaplasia in mice
Blocking IL-17a can improve age-related smell loss in mice.
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research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and balance through specific signaling.
research Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia
Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
research Fibroblast heterogeneity: implications for human disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research MEX3A regulates Lgr5 + stem cell maintenance in the developing intestinal epithelium
MEX3A is crucial for maintaining intestinal stem cells in mice.
research Microfluidic Technology for the Generation of Cell Spheroids and Their Applications
Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
research Tracking adult stem cells
A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
research Mice Engrafted with Human Fetal Thymic Tissue and Hematopoietic Stem Cells Develop Pathology Resembling Chronic Graft-versus-Host Disease
Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
research Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea
Increasing Rps14 helps grow more inner ear cells and repair hearing cells in baby mice.
research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids
Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
research Small Intestinal Organoid-Derived SP Cells Contribute to Repair of Irradiation-Induced Skin Injury
Intestinal stem cells can help repair skin damage from radiation.
research Application and Progress of Cultured Models of Gallbladder Carcinoma
Advancements in cultured models improve understanding and treatment of gallbladder cancer.
research Mouse Spermatogenesis Reflects the Unity and Diversity of Tissue Stem Cell Niche Systems
Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
research Hair follicular cell/organ culture in tissue engineering and regenerative medicine
Stem cell therapy is a promising approach for hair regrowth despite potential side effects.
research Cultured nail keratinocytes express hard keratins characteristic of nail and hair in vivo
Lab-grown nail cells show characteristics similar to natural nail and hair.
research RNA sequence analysis of dermal papilla cells’ regeneration in 3D culture
3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
research Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells
Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research An appraisal of laboratory models of androgenetic alopecia: A systematic review
Better hair loss models needed for research.
research Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling
HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Epidermal stem cells and skin tissue engineering in hair follicle regeneration
Hair follicle regeneration needs special conditions and young cells.
research Adiponectin Signaling Regulates Lipid Production in Human Sebocytes
Adiponectin boosts lipid production in skin cells, potentially helping treat skin conditions with low sebum.
research The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)
Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
research New substrates for stem cell control
New materials help control stem cell growth and specialization for medical applications.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research “Two-Cell Assemblage” Assay: A Simple in vitro Method for Screening Hair Growth-Promoting Compounds
The "Two-Cell Assemblage" assay is a new, simple method to identify substances that may promote hair growth.