147 citations
,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
70 citations
,
November 1984 in “Cell & tissue research/Cell and tissue research” Vitamin D3 affects cell differentiation in specific skin areas.
11 citations
,
August 2000 in “Journal of Endocrinology” DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.
10 citations
,
May 2018 in “Nutrition and Cancer” Certain spices may help prevent and treat skin cancer, but more human trials are needed.
8 citations
,
June 2024 in “APOPTOSIS” Caspases affect many cell functions and could help treat various diseases.
4 citations
,
February 2021 in “Nano select” MSC-Exos can aid organ development and offer therapeutic benefits for various conditions.
22 citations
,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
January 2012 in “heiDOK (Heidelberg University)” Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.
66 citations
,
January 2000 in “Hormone Research in Paediatrics” Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.
48 citations
,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
24 citations
,
May 2021 in “Nature Communications” Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
January 2024 in “Frontiers in immunology” Histone modification is key in treating chronic inflammatory skin diseases.
April 2019 in “Journal of Investigative Dermatology” Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.
326 citations
,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
103 citations
,
March 2011 in “PLoS Biology” Birds can lose neck feathers due to a genetic change that increases a gene's activity, helping them adapt to heat.
101 citations
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August 2010 in “PLoS ONE” Selenoproteins are crucial for healthy skin and hair.
2 citations
,
August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
187 citations
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December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
26 citations
,
January 2014 in “Cell Structure and Function” Human sweat glands contain stem cells capable of self-renewal and forming different cell types.
24 citations
,
May 2018 in “Journal of Molecular Endocrinology” The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
84 citations
,
October 2014 in “PLoS Genetics” Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
49 citations
,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
15 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
4 citations
,
October 2025 in “International Journal of Medical Sciences” Tripeptides help heal wounds and regenerate skin by speeding up tissue repair and reducing inflammation.
January 2015 in “Springer eBooks” Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
Removing SIX1 in fat cells reduces skin fibrosis.
14 citations
,
March 2019 in “Journal of Cosmetic Dermatology” Activated platelet-rich plasma helps hair growth by boosting growth factors and cell growth pathways in hair cells.
8 citations
,
February 2023 in “American Journal of Physiology-Cell Physiology” Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.
2 citations
,
January 2019 in “Biomecánica” Hyaluronic acid and versican are important for skin healing and hair growth and might help in regenerative medicine.