research 적하수오 에탄올 추출물의 melanin 합성 촉진효과
PMEE may help reverse greying hair by boosting melanin production.
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540-570 / 1000+ resultsresearch Supramolecular insights into the complexation of β-Cyclodextrin for alopecia treatment using the mixed cation/anion active principle
This study investigates the formation of a stable inclusion complex between the active ingredient MPPC, found in Minoxicapil®, and β-cyclodextrin (β-CD) for alopecia treatment. Using 1H NMR titration and ROESY experiments, a 1:1 host-guest stoichiometry was identified, with the pyrrolidinyl moiety of MPPC preferentially inserted into the β-CD cavity. Molecular simulations confirmed the stable complex formation, driven by hydrophobic interactions and hydrogen bonding. Strat-M® Franz diffusion studies showed low systemic exposure after 24 hours, and in vitro assays indicated enhanced proliferation of dermal papilla cells (DPCs), supporting the formulation's effectiveness for topical hair-loss treatment.
research Perceptions of Quality Medical Education Among Caribbean Graduate School Administrators, Faculty, and Students that Foster Student Engagement and Achievement
Interactive teaching methods improve student engagement and understanding in medical education.
research A Prospective interventional study on the therapeutic potential of human placental extract in dermatological conditions.
Human placental extract effectively and safely improves melasma, ulcers, and alopecia areata.
research Decoding the ZmNF-YC1–ZmAPRG pathway for phosphorus efficiency
The ZmNF-YC1–ZmAPRG pathway in maize improves phosphorus efficiency and grain yield, suggesting it as a target for breeding better crops.
research Selective isomerization of α-pinene oxide to campholenic aldehyde by ionic liquid-supported indenyl-molybdenum(II)-bipyridine complexes
The process efficiently converts α-pinene oxide to campholenic aldehyde using a special catalyst, achieving high yields quickly.
research Post-Exposure Syndromes as State-Space Trapping: A set-theoretic perspective on PSSD and the post-exposure family.
Post-exposure syndromes are persistent conditions caused by past exposures, needing unique interventions.
research The Combined Use of Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells Promotes Healing. A Review of Experimental Models and Future Perspectives
Using Platelet-Rich Plasma and Adipose-Derived Mesenchymal Stem Cells together can improve healing, including wound healing, bone regeneration, and hair growth.
research Multidisciplinary treatment of obesity with a protein-sparing modified fast: results in 668 outpatients.
A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.
research ALTERAÇÕES MORFOLÓGICAS DA DOENÇA DE PARKINSON UTILIZANDO A RESSONÂNCIA MAGNÉTICA NUCLEAR
research Mite Burden and Immunophenotypic Response to Demodex musculi in Swiss Webster, BALB/c, C57BL/6, and NSG Mice
NSG mice had the most mites, and genetic factors affect immune response and susceptibility.
research Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA
A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research The Function of LPR1 is Controlled by an Element in the Promoter and is Independent of SUMO E3 Ligase SIZ1 in Response to Low Pi Stress in Arabidopsis thaliana
LPR1 regulates root growth under low phosphate stress independently of SIZ1 in Arabidopsis thaliana.
research MmuPV1 infection and tumor development of T cell-deficient mice is prevented by passively transferred hyperimmune sera from normal congenic mice immunized with MmuPV1 virus-like particles (VLPs)
Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.
research Regulation of Hematopoietic Cell Development and Hair Growth in Mouse Models: Expression Analysis of Tudor-SN and Polyamine-Regulated Proteins
Tudor-SN is important for immune cells, and polyamines can promote hair growth.
research Three-dimensional analyses of touch domes in the hairy skin of the cat paw reveal morphological substrates for complex sensory processing
Cat paws have complex touch sensors for detailed sensory processing.
research Dupilumab for prurigo nodularis: real-world outcomes up to 104 weeks from the Dupilumab Italian Prurigo Nodularis (DUPItaPN) study
The Dupilumab Italian Prurigo Nodularis (DUPItaPN) study evaluated the long-term effectiveness and safety of dupilumab in 543 adults with prurigo nodularis (PN) over 104 weeks. The study found that dupilumab significantly improved symptoms, with the mean Worst Itch Numeric Rating Scale (WI-NRS) score decreasing from 8.7 to 1.7, and 86.8% of patients achieving a ≥4-point reduction by week 104. Additionally, 81.2% of patients reached an Investigator Global Assessment for PN-Stage (IGA PN-S) of 0/1. The Dermatology Life Quality Index (DLQI) improved from 17.4 to 2.6. Dupilumab was well tolerated, with only 2.9% discontinuing due to adverse events, and no cancer progression or viral reactivation observed. The study supports dupilumab as a long-term treatment option for moderate-to-severe PN, even in elderly and comorbid patients.
research Cutaneous Focal Mucinosis: A Case Report
A rare skin condition in children can look like other diseases.
research A Comparative Study of Phytochemistry and Pharmacological Attributes of Musa sapientum and Musa paradisiaca
Musa paradisiaca and Musa sapientum have potential health benefits and could be alternatives to synthetic drugs.
research P51 Neuropsychiatric lupus, two sides of the same coin
A thorough, team-based approach and clear communication improve outcomes in complex neuropsychiatric lupus cases.
research Molecular studies of Hutchinson-Gilford progeria syndrome
Suppressing the HGPS mutation may improve symptoms and suggest reversibility.
research Exploring the Role of Uc-Msc-Derived Exosomes in Boosting Hhdpcs Proliferation for Hair Growth Via Akt Activation
UC-MSC-derived exosomes may help treat hair loss by promoting hair cell growth through AKT activation.
research Composite alginate-based hydrogel delivery of antioxidant pumpkin protein hydrolysate in simulated gastrointestinal condition
Combining polysaccharides with alginate improves protection and release of pumpkin seed protein in digestion.
research ACTIVITY OF MEDICINALPLANTS AS IMMUNOBOOSTERS
Tridax procumbens may boost the immune system.
research Disease Prevention and Alleviation by Human Myoblast Transplantation
Myoblast transplantation shows promise for treating various muscle and heart conditions.
research Mucin‐poor follicular mycosis fungoides
The patient's symptoms improved with treatment but recurred when the steroid dose was reduced, requiring ongoing therapy.
research P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression
P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.
research Optimized Methodology to Produce Platelet-Rich Plasma and Perform Platelet Aggregation in Patients With Coronary Artery Disease
A new method improves platelet testing for heart disease patients.
research Polyglandular autoimmune syndrome type 4 with GAD antibody and dystonia
Dystonia may be part of PAS-4 and linked to immune issues.