June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
129 citations
,
January 2007 in “Otology & Neurotology” Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
1 citations
,
January 2019 in “PubMed” cgVEGF164 boosts hair follicle growth in mice.
29 citations
,
January 2010 in “Methods in Enzymology” The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
1 citations
,
December 2025 in “Stem Cell Research & Therapy” Mesenchymal stem cells help heal wounds by using Cx43 hemichannels to improve tissue repair.
March 2026 in “Clinical and Experimental Medicine” Extracellular vesicles are important for disease treatment and monitoring.
39 citations
,
February 2024 in “Small” Microneedles are becoming essential tools in medicine for sensing, drug delivery, and communication.
The curly mutation in SELH/Bc mice affects hair and may help study human genetic disorders.
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
October 2025 in “Journal of Neurophysiology” BK and Kv4.2 channels help Merkel cells in rat whiskers sense touch.
December 2023 in “Aggregate” Scientists are using clumps of special stem cells to improve organ repair.
14 citations
,
July 2022 in “Applied Sciences” Extracellular vesicles can help repair and regenerate tissues with less risk of rejection.
May 2019 in “CINECA IRIS Institutial Research Information System (University of Genoa)” MITF+ melanoma patients are more likely to have multiple melanomas and unique skin patterns.
A new imaging method helps see and study touch nerve endings in mouse skin.
April 2019 in “Journal of Investigative Dermatology” Merkel cell carcinoma is most likely to recur within two years of diagnosis, and factors like immune suppression, being over 75, and male sex increase this risk.
1 citations
,
November 2024 in “eLife” Mesenchymal MEIS2 is essential for whisker development without needing sensory nerves.
24 citations
,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
7 citations
,
August 2023 in “Frontiers in Cardiovascular Medicine” New methods improve stem cell delivery for heart disease, but challenges remain.
5 citations
,
January 2024 in “The International Journal of Developmental Biology” Mouse models help target specific genes in lymphatic cells for research.
3 citations
,
August 2024 in “The Journal of Cell Biology” Actin filaments help stabilize and reshape cell membranes.
August 2011 in “BIO-PROTOCOL”
13 citations
,
January 2015 in “Stem cells international” Mesenchymal Stem Cells (MSCs) are promising for multiple therapies, but more research is needed to fully understand and optimize their use.
April 2021 in “Journal of Investigative Dermatology” Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
17 citations
,
November 2017 in “PLoS ONE” Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.
3 citations
,
December 2024 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)” Spanlastics are effective for delivering Meloxicam with improved stability and targeting.
October 2021 in “Journal of Investigative Dermatology” The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
October 2025 in “International Journal of Molecular Sciences” Extracellular vesicles from mammary cells help heal skin wounds effectively.
August 2018 in “Zenodo (CERN European Organization for Nuclear Research)” New techniques can record electromagnetic fields in hair follicles for potential medical use.
1 citations
,
April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.