133 citations
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May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
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June 2016 in “The anatomical record” Dogs have varying numbers of touch-sensitive Merkel cells in different skin areas, with most in the oral mucosa and facial skin, unrelated to age, sex, breed, or color.
303 citations
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October 2000 in “Nature” RXRα is crucial for hair growth and skin cell function.
April 2012 in “Development” Rac1 is crucial for normal hair structure and pigmentation.
Muscarinic acetylcholine receptors help regulate and promote hair growth.
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October 2006 Matriptase imbalance contributes to cancer development and spread.
27 citations
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September 1999 in “Journal of Investigative Dermatology” Human skin cells contain Protease Nexin-1, and male hormones can decrease its levels, potentially affecting hair growth.
26 citations
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December 2003 in “Experimental Dermatology” Specific keratin gene mutations can cause monilethrix.
February 2025 in “Archives animal breeding/Archiv für Tierzucht” miRNA-211 reduces melanin in Cashmere goats by suppressing AP1S2.
November 2024 in “Communities in ADDI (University of the Basque Country)” Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
March 2026 in “Wound Repair and Regeneration” MARCKSL1 is important for wound healing and could be a target to reduce scarring.
April 2016 in “Journal of Investigative Dermatology” SOX4 is crucial for the development of melanoma.
A specific gene mutation causes monilethrix in this family, and minoxidil treatment improves hair condition.
109 citations
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April 1997 in “Archives of Dermatological Research” Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
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December 2018 in “International journal of environmental research and public health/International journal of environmental research and public health” EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
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June 2024 in “Frontiers in Genetics” Different sheep breeds share similar genetic factors affecting wool fineness.
February 2026 in “BMC Genomics” MEG3-miRNAs help control wool traits in young Tan sheep by regulating immune responses, but their decline with age leads to wool changes.
December 2022 in “Biochemical and Biophysical Research Communications” HtrA2 activity is crucial for normal hair growth by regulating fat cell development.
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January 2000 in “Journal of pharmacopuncture” Microneedle Therapy System effectively treats acne, scars, and hair loss safely.
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May 1999 in “Journal of Biological Chemistry” Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
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July 2017 in “Scientific Reports” JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
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August 2014 in “The FASEB Journal” CAP1/Prss8 does not activate PAR2 or inhibit PN-1.
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August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
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March 2015 in “Clinical and experimental dermatology” Mycophenolic acid may help treat hair loss by promoting hair growth and cell proliferation.
3 citations
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April 2014 in “Journal of Dietary Supplements” CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.
July 2024 in “British journal of dermatology/British journal of dermatology, Supplement” A variant in the KRT31 gene causes a rare hereditary hair disorder called monilethrix.
32 citations
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January 2000 in “Human Heredity” Monilethrix severity varies and may be influenced by other genetic or environmental factors.
May 2017 in “The journal of immunology/The Journal of immunology” Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
16 citations
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May 2006 in “PubMed” Alpha-melanocyte-stimulating hormone helps manage skin inflammation and protect against UV damage.
7 citations
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July 2025 in “Nature Communications” Piezo1 helps skin grow by managing metabolism and inflammation.