Retinoids can cause skin issues and hair loss due to their effects on cell membranes.
31 citations
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February 1982 in “Archives of dermatology” Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.
January 2024 in “Faculty of 1000 Research Ltd” Tazarotene gel may be more effective for acne than adapalene gel.
69 citations
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March 2016 in “American journal of clinical dermatology” Topical retinoids effectively improve photodamaged skin.
April 2002 in “Annals of Internal Medicine” Isotretinoin may increase the risk of high triglycerides and metabolic syndrome, especially in those genetically prone.
66 citations
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January 2017 in “Acta dermato-venereologica” Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
Isotretinoin reduced inflammation in tufted hair folliculitis, but hair tufting remained.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
August 2022 in “Case reports” Isotretinoin effectively treated a rare scalp condition, but careful drug monitoring and a dairy-free diet were important.
3 citations
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January 1990 in “DICP” Minoxidil and tretinoin together may help hair growth but need more research.
December 2024 in “Medicina (Ribeirão Preto)” Adverse reactions to isotretinoin in acne treatment are common and mainly linked to treatment duration.
August 2023 in “Dermatology Reports” Acne not improved by usual treatments may indicate a genetic disorder.
Acitretin treatment unexpectedly darkened a patient's gray hair.
36 citations
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July 2017 in “Journal of controlled release” A new method allows for controlled, long-lasting delivery of retinoic acid through the skin with fewer side effects.
December 2025 in “International Journal of Innovative Technologies in Social Science” Oral supplements like Vitamin E and Omega-3 can help reduce isotretinoin side effects.
4 citations
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September 2006 in “Prescriber” Use topical retinoids for most acne cases, sometimes combined with other treatments.
5 citations
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February 2013 in “Expert Review of Dermatology” New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.
46 citations
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April 1982 in “Journal of the American Academy of Dermatology” Isotretinoin shrinks sebaceous glands without affecting hair or skin color, unlike etretinate.
17 citations
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November 2013 in “Clinical and experimental dermatology” Acitretin therapy may cause hair to repigment and curl.
8 citations
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June 2019 in “Pharmaceutical research” Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.
Acitretin improved monilethrix symptoms temporarily, but they returned after stopping treatment.
2 citations
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January 2014 in “Advanced Biomedical Research” Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.
Delonix polymeric nanoparticles with isotretinoin effectively treat acne by targeting hair follicles and reducing skin irritation.
5 citations
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November 1979 in “Archives of dermatology” Tretinoin cream successfully treated a woman's skin condition called Fox-Fordyce disease.
20 citations
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September 1983 in “Archives of dermatology” The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.
31 citations
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January 1981 in “Pharmacology & Therapeutics” Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
September 2022 in “XXXIX Congresso Brasileiro de Reumatologia” Tofacitinib may effectively treat skin symptoms in difficult cases of dermatomyositis.
July 1988 in “Journal of The American Academy of Dermatology” Various dermatologic treatments were effective for skin conditions like acne, rosacea, hair loss, and psoriasis from December 1986 to December 1987.
July 2024 in “Journal of the American Academy of Dermatology” Oral retinoids like isotretinoin and acitretin can cause significant hair loss.
1 citations
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July 2017 in “Global journal of pharmacy & pharmaceutical sciences” A new hair loss treatment was created using minoxidil and tretinoin in stable niosomes, which effectively released the drugs over time.