research Precision and Personalized Medicine in Transdermal Drug Delivery Systems: Integrating AI Approaches
AI-enhanced smart patches can personalize drug delivery for better treatment outcomes.
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660-690 / 1000+ resultsresearch The Potential Application of Nanocarriers in Delivering Topical Antioxidants
Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.
research Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial – Biochemical)
Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.
research Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment.
Niacin deficiency makes rats more sensitive to cancer-causing chemicals.
research Advanced Applications of Vitamin B Complex in Plastic and Cosmetic Surgery: Mechanisms and Therapeutic Benefits
Vitamin B complex improves plastic and cosmetic surgery outcomes by enhancing tissue repair and reducing inflammation.
research Recent Advances in Multiple Strategies for the Biosynthesis of Sesquiterpenols
Synthetic biology can improve sesquiterpenol production by using innovative microbial strategies.
research Mitochondrial Complex I Activity Suppresses Inflammation and Enhances Bone Resorption by Shifting Macrophage-Osteoclast Polarization
Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.
research Demodicosis in Different Age Groups and Alternative Treatment Options—A Review
Demodex mites are common in adults and elderly, emerging in children, and require careful diagnosis and treatment.
research Retinol dehydrogenase 12 (RDH12): Role in vision, retinal disease and future perspectives
The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.
research Toxic and Metabolic Disorders of the Nervous System
Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.
research The Skin and Inflamm-Aging
Aging skin causes inflammation that affects the whole body.
research Revolutionizing psoriasis care: Microneedle innovations in treatment and diagnosis
Microneedles offer a promising, less invasive way to treat and monitor psoriasis.
research Exploring the Complexities of TGF-beta Signaling in Keloids: Beyond the Classical Smad Pathway
Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
research The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model
Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
research Elevated ornithine decarboxylase activity promotes skin tumorigenesis by stimulating the recruitment of bulge stem cells but not via toxic polyamine catabolic metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research The Impact of Glucagon-like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe?
The effect of GLP-1 RAs on erectile function is unclear and needs more research.
research The Role of PGC-1α in Aging Skin Barrier Function
PGC-1α may improve aging skin by boosting mitochondrial function and reducing inflammation.
research Systems for Mitochondria-Protective Cosmetic Actives: Opportunities in Post-Oncologic Skin Regeneration
Nanocarriers can improve skin treatments after cancer therapy by enhancing antioxidant delivery and effectiveness.
research Metabolic Engineering of Microorganisms to Produce L-Aspartate and Its Derivatives
Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.
research Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives
Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.
research The emerging role of cellular senescence in amyotrophic lateral sclerosis
Cellular senescence may play a role in ALS, and anti-senescence therapies could be a promising treatment.
research Consensus position statement on emerging treatments in dermatology by the Association of Cutaneous Surgeons of India Task Force
Most emerging dermatological treatments lack strong evidence and require more research.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research Real-time iTRAQ-based proteome profiling revealed the central metabolism involved in nitrogen starvation induced lipid accumulation in microalgae
Nitrogen starvation in microalgae increases lipid production, making it a potential biofuel source.
research Two-Stage Machine Learning-Based GWAS for Wool Traits in Central Anatolian Merino Sheep
Machine learning can effectively identify genes to improve wool quality in sheep.
research A Novel Nutraceutical Gummy for Hair Regrowth in Women: A Case Series
The gummy improved hair growth and reduced shedding in women.
research Cordyceps militaris Grown on Germinated Rhynchosia nulubilis (GRC) Encapsulated in Chitosan Nanoparticle (GCN) Suppresses Particulate Matter (PM)-Induced Lung Inflammation in Mice
GCN reduces lung inflammation and damage from air pollution in mice.
research CLED: A Calcium-Linked Protein Associated with Early Epithelial Differentiation
research New Nonsteroidal Molecules as Blockers of the Steroidogenic Pathway
New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
research Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol
Testosterone increases seizure risk through its conversion to specific neurosteroids.