research NEDD4 Transcript Variant 3 and IGF-1 as Molecular Markers in the Development and Prognosis of Keloids
High levels of NEDD4-TV3 and IGF-1 may predict and contribute to keloid formation.
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research Genome-wide association study of skin complex diseases
Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.
research Perspectives of Kennedy's disease
Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.
research SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion
SARS-CoV-2 proteins help the virus avoid the immune system, delaying response and increasing inflammation.
research A comparison of transcriptomic patterns measured in the skin of Chinese fine and coarse wool sheep breeds
Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
research Androgen receptors and their biology
Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
research A genomic approach to susceptibility and pathogenesis leads to identifying potential novel therapeutic targets in androgenetic alopecia
Genomic approach finds new possible treatments for hair loss.
research ARHGEF3 Regulates Hair Follicle Morphogenesis
ARHGEF3 is essential for proper hair follicle development.
research Exploring caspase functions in mouse models
Caspases affect many cell functions and could help treat various diseases.
research YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate
YAP and TAZ proteins control skin cell growth and repair.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
Histone demethylases can change gene expression and may be linked to diseases like cancer.
research Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia
Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
research Fibromodulin reduces scar formation in adult cutaneous wounds by eliciting a fetal-like phenotype
Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
research Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus
The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
research Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing
Deep skin fibroblasts help recruit immune cells for better wound healing.
research Knockdown of FOXA2 Impairs Hair-Inductive Activity of Cultured Human Follicular Keratinocytes
Reducing FOXA2 in skin cells lowers their ability to grow hair.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing
The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
research Combined Deletion of the Vitamin D Receptor and Calcium-Sensing Receptor Delays Wound Re-epithelialization
Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
research Sp6 downregulation of follistatin gene expression in ameloblasts
Sp6 promotes tooth development by reducing follistatin levels.
research Identification of microRNAs involved in growth arrest and cell death in hydrogen peroxide-treated human dermal papilla cells
Targeting specific miRNAs may help treat hair follicle issues caused by hydrogen peroxide.
research Infundibular protein and RNA microarray analyses from affected and clinically non-affected scalp in male androgenetic alopecia patients
Finasteride helps female-pattern hair loss.
research Stem Cells and their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel
Ingenol mebutate gel changes gene expression related to skin development and immune response in actinic keratosis.
research LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells
High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.
research Exploring the Complexities of TGF-beta Signaling in Keloids: Beyond the Classical Smad Pathway
Targeting non-Smad pathways in TGF-β signaling may improve keloid treatment.
research Induction of ferroptosis by natural products in non-small cell lung cancer: a comprehensive systematic review
Natural products may help treat Non-Small Cell Lung Cancer by causing cancer cell death through ferroptosis.
research VDAC2 Mediates the Apoptosis of Cashmere Goat Hair Follicle Stem Cells Through the P53 Signaling Pathway
VDAC2 promotes cell death in cashmere goat hair follicles through the P53 pathway.
research Integrated multiple machine learning and Mendelian randomization reveal LTF gene as a prognostic biomarker for nonspecific orbital inflammation
The LTF gene may help predict and manage nonspecific orbital inflammation.