March 2021 in “CRC Press eBooks” Microneedling helps improve skin and hair by creating tiny, controlled skin injuries.
46 citations
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January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
11 citations
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November 2023 in “Skin Research and Technology” A 2 mm needle is effective and precise for skin injections.
Microneedles could revolutionize pediatric medicine by offering painless drug delivery, but more development is needed.
19 citations
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July 2019 in “Biomedical Microdevices” Microneedles can cause side effects like infection and allergic reactions, and precautions like test spots and sunscreen are recommended.
September 2025 in “Medical Materials Research” Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
39 citations
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February 2024 in “Small” Microneedles are becoming essential tools in medicine for sensing, drug delivery, and communication.
86 citations
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August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
9 citations
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June 2025 in “Frontiers in Pharmacology” Microneedles improve drug delivery, patient compliance, and have potential in cancer treatment and skin care.
4 citations
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May 2019 in “Journal of Cosmetic Dermatology” Using a smaller syringe causes less pain when giving an injection.
4 citations
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January 2022 in “Yonsei Medical Journal” Microneedles are a promising method for drug delivery, offering efficient and convenient alternatives with fewer side effects.
17 citations
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May 2023 in “Pharmaceutics” Microneedles can precisely deliver cancer treatments with fewer side effects.
2 citations
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March 2024 in “Pharmaceutics” The placebo microneedle stamp didn't penetrate skin and caused less pain, but blinding was only effective for those with low skin sensitivity.
13 citations
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April 2001 in “Journal of The American Academy of Dermatology” Using a vibrating device during injections can help reduce pain.
September 2024 in “Journal of Cosmetic Dermatology” Cold gel compresses are the best for pain relief during scalp microneedling.
April 2020 in “Journal of The American Academy of Dermatology” Microneedling with platelet-rich plasma can cause temporary, painful lymph node swelling in some patients.
3 citations
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May 2011 in “International Journal of Dermatology” Using an epidural needle in hair restoration surgery can reduce grafts popping out, make the procedure easier, and result in natural-looking hairlines without obvious scarring.
39 citations
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June 2023 in “Advanced Materials” Microneedles offer a promising, painless, and efficient way to deliver vaccines and therapies directly to the skin.
61 citations
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April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
30 citations
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November 2024 in “ACS Materials Au” Microneedles are promising for disease monitoring and drug delivery due to their minimal invasiveness and versatility.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” Microneedling helps increase the absorption of a melanin product into hair follicles, which may improve laser hair removal effectiveness.
3 citations
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January 2019 in “Česká a slovenská farmacie” Microneedles could make it easier and less painful to deliver more types of drugs through the skin.
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Microneedles offer a painless way to deliver drugs effectively but need more research before they can be widely used.
4 citations
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December 2022 in “Infection and Drug Resistance” Fire needle therapy is an effective and better alternative to surgery for early-stage neck carbuncles.
March 2025 in “Pain Physician” Cooling the skin before injections reduces pain for patients with hair loss.
May 2023 in “Current Medicinal Chemistry” Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
7 citations
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September 2018 in “Journal of cosmetic dermatology” A patient had painful swollen lymph nodes after a cosmetic skin and hair treatment, suggesting doctors should warn about this risk.
17 citations
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August 2021 in “Dermatologic surgery” Microneedling is generally safe but can cause minor, temporary side effects and requires caution for some patients.
55 citations
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March 2018 in “Journal of pharmacy & pharmaceutical sciences” Microneedles help improve drug delivery through the skin and are used in medicine and beauty treatments.
131 citations
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May 2015 in “Experimental Dermatology” Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.