7 citations
,
August 2025 in “Journal of Nanobiotechnology” Bioengineered microneedles and nanomedicine offer promising, precise treatments for tissue regeneration.
4 citations
,
September 2024 in “Cell Reports” Granulocyte colony stimulating factor helps heal wounds without scars.
2 citations
,
April 2023 in “Stem Cell Research & Therapy” Tiny fat-derived particles can help repair soft tissues by changing immune cell types.
January 2026 in “Bioengineering” Recombinant collagen is promising for biomaterials, pharmaceuticals, and skincare due to its benefits and potential improvements.
June 2025 in “Proceedings of the National Academy of Sciences” A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
May 2023 in “Antioxidants” Peptides from oysters may safely and effectively heal skin wounds with less scarring.
July 2023 in “International Journal of Cosmetic Science” Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.
December 2024 in “Journal of Cosmetic Dermatology” Exosomes from platelet-rich plasma may help heal wounds but need more research for hair growth and skin use.
338 citations
,
July 2009 in “Development” Sox2-positive cells determine specific hair follicle types in mammals.
171 citations
,
June 2004 in “Journal of Investigative Dermatology” GLI2 activates GLI1, promoting skin tumor growth and hair development.
159 citations
,
January 2006 in “BMC Cell Biology” Wnt signaling can improve skin healing by promoting epithelial growth.
136 citations
,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
136 citations
,
April 2010 in “British Journal of Dermatology” Acitretin is effective for severe skin conditions but has significant side effects and requires careful monitoring.
114 citations
,
August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
91 citations
,
June 2011 in “The EMBO Journal” TCF/Lef1 activity is essential for proper skin cell development and renewal.
83 citations
,
December 2012 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.
78 citations
,
November 2005 in “Endocrinology” Hairless protein can block vitamin D activation in skin cells.
61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
56 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle cells age faster and lose pigment due to less catalase, causing hair to turn gray.
50 citations
,
August 2021 in “Stem Cell Research & Therapy” Adipose-derived stem cells help heal radiation skin damage by reducing cell death and inflammation.
49 citations
,
November 2016 in “Frontiers in Pharmacology” Tripterygium wilfordii Hook F often causes side effects like stomach issues and skin reactions.
49 citations
,
August 1999 in “Journal of Investigative Dermatology” Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.
46 citations
,
December 1998 in “Journal of Biological Chemistry” Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
38 citations
,
April 2017 in “PLOS Genetics” GRHL3 is important for controlling gene activity in skin cells during different stages of their development.
34 citations
,
July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
30 citations
,
November 2015 in “Advanced Pharmaceutical Bulletin” Nanoethosomes can improve the skin penetration of Lidocaine for topical use.
30 citations
,
February 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Plet-1 protein helps hair follicle cells move and stick to tissues.
25 citations
,
November 2022 in “Frontiers in Bioengineering and Biotechnology” Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.
18 citations
,
November 2016 in “PeerJ” Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
16 citations
,
October 2004 in “Journal of Investigative Dermatology” Normal human melanocytes can avoid cell death through multiple pathways.