research Aging of hair follicle stem cells and their niches
Aging changes hair stem cells and their environment, leading to gray hair and hair thinning, but understanding these changes could help develop treatments for hair regeneration.
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research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA ‐sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research Induction of cardiomyocyte‑like cells from hair follicle cells in mice
Mouse hair follicle cells can become heart-like cells without genetic changes.
research LSD1 is Required for Hair Cell Regeneration in Zebrafish
LSD1 is crucial for regenerating hair cells in zebrafish.
research Do we need hair follicle stem cells and hair follicle neogenesis to cure common hair loss disorders?
Common hair loss disorders may not need stem cell therapy, but could benefit from other treatments like hair cycle control and immune restoration therapy.
research Live imaging of skin immunity using two-photon microscopy: a short review
Two-photon microscopy improves skin imaging but faces safety and cost challenges for clinical use.
research Force-triggered density gradient sedimentation and cocktail enzyme digestion treatment for isolation of single dermal papilla cells from follicular unit extraction harvesting human hair follicles
A new method improves the isolation of hair follicle cells for better hair growth research.
research An optimized force-triggered density gradient sedimentation method for isolation of pelage follicle dermal papilla cells from neonatal mouse skin
New method efficiently isolates hair growth cells from newborn mouse skin.
research 1418 Characterization of ectomesenchyme as an origin of epidermal stem cells
Ectomesenchyme is a key source of skin stem cells.
research Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
research Keratins of the human hair follicle: “Hyperproliferative” keratins consistently expressed in outer root sheath cells in vivo and in vitro
Outer root sheath cells consistently express certain keratins influenced by their environment.
research Cell-repellent polyampholyte for conformal coating on microstructures
Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.
research 851 The role of astrotactin2 in regulating mammalian skin polarity
Astrotactin2 affects hair follicle orientation and skin cell polarity.
research Acute Stroke After Scalp Injection of Platelet Rich Plasma and Stem Cells for Hair Loss
A man had a stroke after getting a scalp injection for hair loss.
research P62 Pre-clinical pharmacological and skin penetration profile of LDE255, a novel and specific Smoothened antagonist
LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
research Distribution pattern of some glycoconjugates of hair follicle regeneration in rat
Certain sugars increase in some layers of the hair follicle during the middle of the healing process in rats, which may help improve healing.
research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Hepatocyte growth factor-modified hair follicle stem cells ameliorate cerebral ischemia/reperfusion injury in rats
HGF-modified hair follicle stem cells help brain recovery after injury in rats.
research Stem Cells from Human Exfoliated Deciduous teeth Promote Hair Regeneration in Mouse
Baby teeth stem cells can help grow hair in mice.
research Biology of melanocytes in mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
research Epidermal Stem Cells in Orthopaedic Regenerative Medicine
Epidermal stem cells show promise for treating orthopedic injuries and diseases.
research In vitro Differentiation of Adipose-Derived Stem Cells into Hair Cell-Like Cells in Guinea Pigs
Guinea pig fat stem cells can become hair cell-like cells in a lab.
research Multiple cell types guided by neurocytes orchestrate horn bud initiation in dairy goats
Nerve cells and other cell types work together to start horn growth in dairy goats.
research Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia
Schizophrenia risk genes may affect early brain development, contributing to the disease.
research The Hair Follicle as a Dynamic Miniorgan
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Molecular principles of hair follicle induction and morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle
Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research Regeneration of skin appendages and nerves: current status and further challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.