research Rejuvenation: an integrated approach to regenerative medicine
Rejuvenating self-repair mechanisms could improve organ recovery in regenerative medicine.
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research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Advances in Innovative Surgical Implant Manufacturing for Hernia Repair and Soft Tissue Reconstruction
Coating surgical meshes with PRP may improve hernia repair outcomes.
research Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing
Softer hydrogels help wounds heal better with less scarring.
research The stem cell niche
Stem cell niches are essential for tissue health and repair.
research Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling
β-catenin, Shh, and Bmp signaling control hair follicle development.
research Spatial relationship between Merkel cells and Langerhans cells in human hair follicles
Merkel cells and Langerhans cells in hair follicles are closely connected and may interact.
research Adaptive Balance in Posterior Cerebellum
The posterior cerebellum helps maintain balance by adapting to sensory inputs and self-motion.
research The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice
Neurosteroids in the brain can increase or decrease seizure risk in mice.
research Novel insights into the molecular mechanisms underlying generalized glucocorticoid resistance and hypersensitivity syndromes
Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.
research Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells
Nerve growth factor helps improve healing time and scar quality in burn wounds.
research The gut‐microbiota‐brain axis: Focus on gut steroids
Gut bacteria affect steroid levels, influencing health conditions and potential treatments.
research A Chemically Defined Culture for Tooth Reconstitution
A new culture system can grow tooth-like structures from dental cells but can't yet develop roots.
research Mitochondrial dysfunction in diabetic neuropathy may be involved in the development of neuropathic pain via a reduction in neurosteroid synthesis
Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.
research Hair Regeneration Methods Using Cells Derived from Human Hair Follicles and Challenges to Overcome
Current hair regeneration methods show promise but face challenges in maintaining cell effectiveness and creating the right environment for hair growth.
research ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth
ISX9 helps regrow hair by activating a specific cell signaling pathway.
research Efficacy, safety, and patient-reported outcomes of scalp micropigmentation in scarring alopecia
Scalp micropigmentation improves appearance and satisfaction in scarring alopecia but may require repeat sessions.
research Importance of dietary supplementation of soluble and insoluble fibers to sows subjected to high ambient temperatures during late gestation and effects on lactation performance
Adding both soluble and insoluble fibers, especially beet pulp, to the diet of pregnant sows helps improve their health and the growth of their piglets in hot weather.
research Cells and Structures Involved in Hair Follicle Regeneration: An Introduction
The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
research Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3
Protein Kinase Cε increases skin sensitivity to UV damage and skin cancer risk.
research Fibroblasts: Immunomodulatory factors in refractory diabetic wound healing
Fibroblasts are important in healing diabetic wounds, but high sugar levels can harm their function and slow down the healing process.
research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology
3D human skin models show promise for dermatology but face challenges in standardization and cost.
research 3D-printed porous functional composite scaffolds with polydopamine decoration for bone regeneration
The scaffold with polydopamine and bioactive glass effectively promotes bone regeneration.
research The JAK/STAT signaling pathway: from bench to clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro?
Creating fully functional artificial skin for chronic wounds is still very challenging.
research Artificial intelligence: revolutionizing robotic surgery: review
AI in robotic surgery improves precision and safety but faces cost and ethical challenges.
research Cell fate decisions: emerging roles for metabolic signals and cell morphology
Metabolic signals and cell shape influence how cells develop and change.
research Recent Advances in Biopolymeric Composite Materials for Tissue Engineering and Regenerative Medicines: A Review
Biopolymeric composites need advanced properties for better use in medicine and healing.
research Development of Heritable Melanoma in Transgenic Mice
The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
research Advanced Intelligent Systems for Surgical Robotics
Surgical robots have improved but still can't perform tasks or make decisions on their own.