research Cognitive effects of testosterone and finasteride administration in older hypogonadal men.
Testosterone improves mood and thinking skills; finasteride has no effect.
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research Empathic disequilibrium is related to lower levels of oxytocin in hair
People with an imbalance between their cognitive and emotional empathy have lower levels of the hormone oxytocin in their hair.
research Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation
Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers criticized the study for assuming drugs with similar side-effects work the same way and questioned the validity of its findings due to potential biases and data quality issues.
research The importance of the neuro‐immuno‐cutaneous system on human skin equivalent design
Human skin models are essential for studying skin's sensory, immune, and nervous system interactions.
research Effects of local and systemic medications on eye health: Adverse reactions
Medications can cause eye problems, so regular eye check-ups are important.
research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles
Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
research CHEMISTRY AND SIGNIFICANCE OF CHEMOPREVENTIVE NUTRACEUTICALS: A REVIEW
Nutraceuticals may help prevent cancer and work best in combination with other compounds.
research Transcriptome profiling of whisker follicles in methamphetamine self-administered rats
Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.
research Therapeutic Effects of Natural Products on Human Diseases
Natural products can safely and effectively treat various human diseases.
research Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity
New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.
research The Relationship Between Glycine and Gephyrin in Synapses of the Rat Spinal Cord
Glycine is a key transmitter in rat spinal cord synapses, often alongside GABA.
research Biological effects of human placental extracts - variations in manufacturing methods and compositions
Placental extracts have antioxidant, anti-inflammatory, and immune-boosting effects, but their exact workings are unclear.
research 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration
4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
research Long-term effects of chemotherapy in children with cancer
Chemotherapy in children often causes hair loss, nausea, vomiting, and mood swings.
research Advancements in Drug Repurposing: Examples in Psychiatric Medications
Old psychiatric drugs are increasingly being used for new purposes, and technologies like SmartCube® help create new drugs.
research Pathological findings in a case of stiff person syndrome with anti‐GAD antibodies
Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.
research Efeitos do tratamento prolongado de testosterona associado ao uso de algestona acetofenida e enantato de estradiol sobre o ciclo menstrual de fêmeas cativas de Sapajus libidinosus (macaco-prego)
The treatment changed hormone levels and increased sexual behavior in female capuchin monkeys.
research Anti-nociceptive and anti-inflammatory properties of 5alpha-reductase inhibitor finasteride in experimental animals
Finasteride helps reduce pain and inflammation in animals.
research Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons.
A soluble factor in developing mouse whisker pads boosts nerve growth factor mRNA production.
research Influence of conditioned media from glial cell cultures on contractility of uterine in rats of different ages
Conditioned media from glial cell cultures improved uterine contractions in older rats.
research Patient-reported Outcomes of Adverse Events After Perioperative Chemotherapy for Breast Cancer: A Prospective Observational Study
Some side effects of breast cancer chemotherapy, like neuropathy and nail loss, can last long after treatment.
research The Effects of Perinatal Androgen Deprivation on Body Weight and Spatial Working Memory in Male Rats
Blocking male hormones in baby rats improved memory and increased weight.
research Mast cell-5-HT-HTR2A axis involvement in chronic itch induced by SADBE
Targeting the MC-5-HT-HTR2A axis may help treat chronic itching.
research Sensations Evoked by Microstimulation of Single Mechanoreceptive Afferents Innervating the Human Face and Mouth
Microstimulation of certain facial and mouth nerves can evoke specific sensations, while deeper nerves may require multiple stimulations to affect perception.
research Hair Metal Dysregulation in Parkinson's Disease: Implications for Diagnosis and Gut-Brain Axis Involvement
research In-vivo Assessment of Neuropharmacological Activity of Methanol Bark Extract of Mimosa Pudica in Mice
Mimosa pudica extract may help create new sedative and anti-anxiety drugs.
research Relationships between hair-follicle afferent axons and glycine-immunoreactive profiles in cat spinal dorsal horn
Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
research Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor
New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.
research Cognitive effects of testosterone and finasteride administration in older hypogonadal men
Testosterone and finasteride showed minor cognitive benefits in older men.