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,
February 2004 in “Biopolymers” 4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
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,
April 2007 in “Neuroscience” Reducing neurosteroid levels worsens brain injury in fetal sheep.
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6 citations
,
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Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.
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Early NAS level changes affect alcohol consumption vulnerability.
January 2015 in “Annual Research & Review in Biology” Natural antioxidants and phytotherapeutic molecules may help prevent cancer.
3 citations
,
April 2009 in “PubMed” Melatonin may protect rat hair follicles from damage caused by oxidative stress after a burn.
50 citations
,
July 1996 in “Cell” Chromosomal changes, including those in the WRN gene and rDNA, may significantly contribute to aging.
28 citations
,
August 2015 in “Journal of Drug Targeting” The new CoQ10 gel protects mouse skin better against aging from UV light than the old gel.
2 citations
,
March 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” HAIR may cause fetal loss by triggering different cell death processes in the uterus and placenta.
2 citations
,
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9 citations
,
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2 citations
,
June 1985 in “PubMed” Ethylenthiourea is toxic to the liver and nervous system, especially with alcohol.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
1 citations
,
December 2005 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” Melatonin reduced oxidative stress and might improve hair growth in alopecia areata patients.
19 citations
,
January 2012 in “Frontiers in Neural Circuits” Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
September 2025 in “Dietary Supplements and Nutraceuticals” Cerebronal® may help improve certain brain health markers.
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May 2004 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease” Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
May 2026 in “BMC Medicine” ACOD1 deficiency worsens hair loss by causing cell aging and mitochondrial problems, but 4-OI may help.
11 citations
,
January 2006 in “Journal of the American Leather Chemists Association” Oxidizing agents break down keratin in wool and hair, causing swelling and increased solubility.
January 2026 in “Aging and Disease” Targeting mitochondria can improve skin health and slow aging.
18 citations
,
April 2024 in “Phytotherapy Research” Plant-based compounds show promise for treating neurodegenerative diseases but need more research.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Stress in hair follicle cells increases certain immune-related proteins, which might contribute to hair loss conditions.
January 2023 in “Brazilian Journals Editora eBooks” Surgery to fix a broken upper arm bone can sometimes lead to nerve damage.
2 citations
,
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