37 citations
,
October 2021 in “Journal of Clinical Investigation” Skin inflammation can worsen intestinal inflammation and colitis.
April 2026 in “Journal of Dermatology Research” The skin communicates with the nervous system, and targeting neurohormones like melatonin and oxytocin could help treat skin issues.
September 2023 in “Research Square (Research Square)” TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
28 citations
,
January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders” Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
September 2025 in “Dicle Medical Journal / Dicle Tip Dergisi” Skin issues are common in people with neurodegenerative diseases.
8 citations
,
October 2013 in “The Journal of Spinal Cord Medicine” Most spinal cord injury patients in Korea experience skin problems, especially fungal infections and eczema, affecting their quality of life.
34 citations
,
July 2006 in “The Journal of Comparative Neurology” Increasing neurotrophin 4 in skin boosts nerve endings but not sensory neuron count.
9 citations
,
June 2017 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Local inflammation worsens autoimmune skin conditions by increasing antibody buildup.
Reducing nerve growth can help skin regenerate after birth.
88 citations
,
May 2020 in “Clinical therapeutics” Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.
January 2025 in “Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)” Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
November 2025 in “PLoS ONE” Nucleic acids trigger chemokine production in skin cells, affecting skin inflammation.
34 citations
,
August 2005 in “Dermatologic Clinics” Stress and emotional factors can worsen skin conditions by affecting the immune system.
60 citations
,
November 2023 in “Biology” Aging skin causes inflammation that affects the whole body.
January 2021 in “Springer eBooks” Different rheumatological diseases can cause specific skin problems.
The skin plays a key role in immune responses and reflects emotional and stress reactions.
September 2004 in “Experimental Dermatology” Stress and certain chemicals affect hair growth by interacting with the immune and nervous systems.
January 2016 in “Vojnosanitetski Pregled” Some treatments for inflammatory bowel disease can cause skin problems like rashes and melanoma.
May 2022 in “Голова и шея.” Checkpoint inhibitor therapy can cause skin issues, from mild rashes to severe reactions.
3 citations
,
May 2023 in “Frontiers in immunology” Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
7 citations
,
July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin can be reconnected to nerves using stem cells, which may help with skin health and healing.
October 2025 in “Journal of Applied Genetics” Autoinflammatory skin diseases are complex, increasingly common, and significantly affect quality of life.
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
November 2024 in “Journal of Investigative Dermatology” Nerve fibers may worsen mast cell activity, leading to abnormal elastic fiber buildup from sun exposure.
January 2013 in “Open journal of gastroenterology” Ulcerative colitis can cause skin issues due to immune system problems.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
January 2016 in “International Journal of Dermatology and Venereology” DNA methylation changes are linked to skin diseases with inflammation.
2 citations
,
February 2018 in “InTech eBooks” TNF-alpha inhibitors can cause various immune-related skin issues.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.