research Regeneration Genetics
Understanding tissue regeneration in animals can improve regenerative medicine.
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360-390 / 1000+ resultsresearch Allopregnanolone, the active metabolite of progesterone protects against neuronal damage in picrotoxin-induced seizure model in mice
research Neurotrichosis: Hair‐shaft Abnormalities associated with Neurological Diseases
Hair-shaft abnormalities can indicate neurological disorders, some of which are treatable.
research Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.
research Hypoxia and metabolic adaptation drive self-organization in organoid morphogenesis and tissue regeneration
research 細胞配置と力学的刺激の複合効果がもたらす毛髪および皮膚附属器官の完全生体外再生
Hair follicles and skin structures were successfully regenerated in the lab using specific cell arrangements and mechanical conditions.
research Cell Cycle Regulation and Regeneration
Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
research miR‐124 promotes neural differentiation in mouse bulge stem cells by repressing Ptbp1 and Sox9
miR-124 helps mouse hair follicle stem cells become nerve cells by blocking Ptbp1 and Sox9.
research Single-Cell Transcriptomics to Map Cellular Heterogeneity in Tissue Regeneration Models
Single-cell transcriptomics reveals detailed cellular diversity and key pathways in tissue regeneration.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research ‘Neurotrophology’ of the hair follicle: neurotrophins act as auto‐ and paracrine growth factors and immunomodulators
Neurotrophins are important for hair growth and response to stress.
research Editorial overview: Embroidering the canvas of life
The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
research Engineering the niche for hair regeneration — A critical review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research The Opening of Potassium Channels: A Mechanism for Hair Growth
research Role of the nail and dorsoventral patterning in regeneration
Nails are essential for fingertip regeneration.
research Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures
Progesterone and testosterone protect brain cells from damage through specific pathways.
research Functional Hair Follicle Regeneration by the Rearrangement of Stem Cells
Stem cells rearrangement regenerates functional hair follicles, potentially treating hair loss.
research Stem cell dynamics, migration and plasticity during wound healing
Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.
research The Role of miR-214-3p in Hair Follicle Neural Crest Stem Cell-derived Exosomes in the Repair of Peripheral Nerve Injury
miR-214-3p helps nerve repair and recovery.
research 329 In vitro co-culture models of merkel cell-neurite complex in touch domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research The bright side of fibroblasts: molecular signature and regenerative cues in major organs
Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.
research Exosomes in stroke management: A promising paradigm shift in stroke therapy
Exosome therapy could revolutionize stroke treatment, but more research is needed for human use.
research Rational Design and Functionalization of Melt Electrowritten 4D Scaffolds for Biomedical Applications
4D scaffolds made with melt electrowriting can change shape for use in medicine.
research Faculty Opinions recommendation of Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding.
Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.
research Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100
Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
research Embryonic development of hair follicle pluripotent stem (hfPS) cells
research Evaluating purified exosome product and its role in neurologic and functional recovery following spinal cord injury in female rats
IT PEP may help recovery after spinal cord injury, but more research is needed.
research Panel Session
Long-term alcohol exposure alters brain receptor function differently in various brain regions.
research Reprogramming of Aged Dermal Papilla Cells in Vitro: In Silico Insight into the Biomarkers of Hair Growth and Tissue Repair
Aging dermal papilla cells can be reprogrammed for potential hair growth and skin repair.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.