research Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation
NIPP1 is important for healthy skin and could help treat skin inflammation.
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research A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling
A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
research 1407 Mechanical force activation of TGF-β signaling controls hair follicle regression
Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.
research Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice
Progesterone reduces anxiety and depression in female mice by increasing BDNF in the brain, needing 5α-reduction and estradiol.
research Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress
Caloric stress and differentiation increase IRES translation, affecting stem cell function and potential therapies.
research Modulating mechanosensory afferent excitability by an atypical mG luR
A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.
research Compartmentalized organization: a common and required feature of stem cell niches?
Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
research Abstract 2962: Chemotherapy induced senescence drives peripheral neuropathy
Eliminating senescent cells can prevent and reverse chemotherapy-induced peripheral neuropathy.
research Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin
Hair follicle development and microbes help regulatory T cells gather in newborn skin.
research MicroRNA-205 promotes hair regeneration by modulating mechanical properties of hair follicle stem cells
MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
research Implications of neuroimaging for the treatment of epilepsy
Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.
research Regulatory T Cells in Autoimmune Diseases and their Potential
Enhancing regulatory T cells may help treat autoimmune diseases like alopecia areata.
research Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model
Human hair keratin helps repair nerve damage in rats.
research Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles
Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
research Harnessing mechanobiology for hair regeneration: Emerging techniques and therapies
New techniques like electrical stimulation and microneedling may improve hair growth and offer alternatives to current treatments.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Nerve growth factor and burn wound healing: Update of molecular interactions with skin cells
Nerve growth factor helps improve healing time and scar quality in burn wounds.
research The Role of LncRNAs in Radio- and Chemoresistance of Glioblastoma: Prognostic or Therapeutic?
LncRNAs may help improve brain cancer treatment and diagnosis.
research Wnt Signaling Across Adult Skin Mini-Organs: Interfollicular Epidermis, Hair Follicle, and Nail—Implications for Disease and Regeneration
Wnt signaling is crucial for skin, hair, and nail health and regeneration.
research Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice
Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.
research Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers
Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.
research Regulation of stem cell fate by HSPGs: implication in hair follicle cycling
HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
research Nail Proximal Fold Stem Cells (NPFSCs) Participate In Nail Growth, Orchestrating Enhanced Digit Regeneration via BMP Signaling Activation
Nail stem cells help nail and finger regeneration through BMP signaling.
research Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation
BMP and Wnt signaling balance controls hair follicle stem cell activity and hair growth.
research The protease corin regulates electrolyte homeostasis in eccrine sweat glands
Corin helps control salt and sweat release in sweat glands.
research Integrative analysis reveals ncRNA-mediated molecular regulatory network driving secondary hair follicle regression in cashmere goats
Non-coding RNAs help control hair growth cycles in cashmere goats, suggesting ways to improve cashmere production.
research Cell cycle controls long-range calcium signaling in the regenerating epidermis
Calcium signaling in skin cells is crucial for communication and regeneration.
research 2‐Deoxy‐d ‐glucose enhances tonic inhibition through the neurosteroid‐mediated activation of extrasynaptic GABA A receptors
2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.