November 1999 in “Australasian Journal of Dermatology” The document concludes that there is a need for more research and regulation in dermatology, covering topics like latex allergy in children, the use of botulinum toxin, and treatments for skin conditions.
7 citations
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April 2002 in “Science” Botulinum toxin, once seen as a poison, is now used to treat medical conditions and is unlikely to be an effective biological weapon.
1 citations
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June 2025 in “Pharmacia” Botulinum toxin is effective for medical and cosmetic uses but requires careful handling to avoid serious side effects.
2 citations
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June 1985 in “PubMed” Ethylenthiourea is toxic to the liver and nervous system, especially with alcohol.
December 2025 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” Botulinum toxin may reduce inflammation markers in head and neck conditions, but evidence is uncertain.
9 citations
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July 2024 in “Toxins” OnabotulinumtoxinA is used to treat wrinkles, pain, sweating, hair loss, and more by temporarily paralyzing muscles and affecting pain pathways.
19 citations
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January 2012 in “Frontiers in Neural Circuits” Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.
189 citations
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May 1999 in “Microscopy Research and Technique” Neurotrophins, especially NGF, are crucial for pain development and management.
23 citations
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September 2021 in “Clinical Cosmetic and Investigational Dermatology” Botulinum toxin is used in skin care for cosmetic and medical purposes.
34 citations
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November 1991 in “Choice Reviews Online” Neurons and synapses are key to brain function and learning.
July 2005 in “CME: Your SA Journal of CPD” Botulinum toxin is a safe alternative for treating migraines without common side effects, but should be used after other treatments fail.
Bioactive compounds in neurocosmetics can improve skin health and emotional well-being.
April 2023 in “Journal of Investigative Dermatology” Using DNase enzymes to break down harmful NETs could be a new treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis.
April 2016 in “Journal of Investigative Dermatology” Microneedle arrays deliver botulinum toxin effectively for sweat suppression, similar to injections.
January 2018 in “Computational Toxicology” Pharmacophore models can predict liver toxicity and central nervous system toxicity, but they have limitations and specific requirements.
80 citations
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December 1996 in “Pain” Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.
February 2005 in “Journal of The American Academy of Dermatology” Doctors should recognize various nail disorders, new allergens, and metabolic syndrome in patients, and use botulinum toxin carefully in aesthetic procedures.
52 citations
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January 2023 in “Toxins” Botulinum toxin can safely and effectively treat facial wrinkles and muscle issues with precise injection techniques.
122 citations
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June 1998 in “PubMed” Neurotrophins regulate nerve growth by balancing promotion and suppression.
11 citations
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September 2011 in “Biochemical journal” Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
10 citations
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August 2024 in “Neuroscience & Biobehavioral Reviews” Neurosteroids may help treat disorders with too much dopamine activity.
26 citations
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April 2006 in “Cephalalgia” Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.
The data suggests that dosing differences can help manage spasticity in patients with upper motor neuron dysfunction.
January 2024 in “Wiadomości Lekarskie” Combining standard treatment with exogenous cholinesterases can improve outcomes in severe organophosphate poisoning.
18 citations
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April 2024 in “Phytotherapy Research” Plant-based compounds show promise for treating neurodegenerative diseases but need more research.
March 2024 in “European Journal of Neuroscience” Dopaminergic neurons in the gut have diverse subtypes with different neurotransmitter contents.
44 citations
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October 2016 in “Epilepsia” 2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.
June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Dopaminergic neurons in the gut have distinct subtypes, some releasing both dopamine and acetylcholine.
June 2007 in “Emergency medicine news” If someone has unexplained nerve pain and hair loss, doctors should check for thallium poisoning.
34 citations
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July 2006 in “The Journal of Comparative Neurology” Increasing neurotrophin 4 in skin boosts nerve endings but not sensory neuron count.