23 citations
,
January 2021 in “Biomedicine & Pharmacotherapy” DHT stops hair regrowth in mice, similar to human hair loss.
17 citations
,
May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
17 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.
14 citations
,
July 2016 in “Anatomical Science International” The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
13 citations
,
February 2018 in “Bio-medical Materials and Engineering” Minoxidil inside tiny particles can deliver more drug to hair follicles, potentially improving treatment for hair loss.
12 citations
,
November 2003 in “Journal of the American Academy of Dermatology” Topical diphencyprone helped regrow hair in mice and rats with a condition similar to human hair loss.
10 citations
,
June 2018 in “Aaps Pharmscitech” The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
8 citations
,
July 2020 in “International Journal of Pharmaceutics” Finasteride's solubility improves with native y-CDs, enhancing hair loss treatment and reducing side effects.
4 citations
,
February 2022 in “Frontiers in molecular biosciences” Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
4 citations
,
December 2016 in “Journal of Pakistan Association of Dermatology” Using isotretinoin gel and minoxidil solution together effectively regrows hair in most people with patchy hair loss.
4 citations
,
December 2014 in “European Journal of Chemistry” Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.
3 citations
,
May 2025 in “Frontiers in Pharmacology” Vismodegib can cause muscle spasms, taste changes, hair loss, fatigue, weight loss, and possibly new issues like skin cancer, dehydration, and swallowing problems, needing close monitoring.
1 citations
,
March 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications” Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.
September 2022 in “Institutional Repositories DataBase (IRDB)” 3D-oxy exosomes may significantly boost hair growth, offering new treatment options for hair loss.
July 2013 in “Our Dermatology Online” Minoxidil 2% is more effective than tacrolimus 0.1% for hair regrowth in mild to moderate patchy hair loss, and combining both might give better results.
October 2020 in “Journal of Pharmaceutical Sciences” Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
193 citations
,
August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
36 citations
,
April 2016 in “British journal of dermatology/British journal of dermatology, Supplement” A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
20 citations
,
September 1978 in “International Journal of Dermatology” Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.
9 citations
,
July 2017 in “Journal of Drug Delivery Science and Technology” Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
2 citations
,
February 2004 in “Biopolymers” 4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.
April 2026 in “International Journal of Drug Delivery Technology” Alopecia can often be managed effectively with various treatments, but early diagnosis is crucial for preventing permanent hair loss.
January 2026 in “Frontiers in Pharmacology” Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
January 2020 in “Química Nova” The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.
May 2025 in “Scientific Reports” Oxyresveratrol promotes hair growth and may help treat hair loss.
Hair loss can occur after treating diabetic ketoacidosis, especially with rapid weight loss and high soft drink intake.
January 2025 in “Nanoscale” Boron/nitrogen-doped carbon nano-onions improve targeted breast cancer treatment by enhancing drug delivery and reducing side effects.
1 citations
,
October 2025 in “Journal of Allergy and Clinical Immunology” A JAK1 variant causes hair loss, skin issues, and thyroid disease, but treatment with a specific inhibitor can help.