10 citations
,
November 2009 in “Pigment cell & melanoma research” The document concludes that MGRN1 affects mouse fur color by interfering with a receptor's signaling, but its full role in the body is still unknown.
Melanocyte transplantation can safely restore skin color, especially in stable vitiligo, but must be chosen carefully based on the disease phase.
January 2006 in “Carl von Ossiezky University of Oldenburg” Unpigmented keratinocytes absorb substances faster, while melanocytes bind more strongly to melanin.
23 citations
,
April 2004 in “American Journal of Ophthalmology” Using bimatoprost on one side of the face caused increased cheek hair growth in a patient.
17 citations
,
September 2018 in “Matrix Biology” Laminin-511 is essential for proper melanocyte movement and development in mice.
15 citations
,
March 2004 in “American Journal of Ophthalmology” Using bimatoprost on one side of the face caused increased cheek hair growth in a patient.
8 citations
,
December 1997 in “International Journal of Dermatology” The patient has a leg condition caused by vein issues, needing lifestyle changes and leg care.
1 citations
,
January 2014 in “Elsevier eBooks” Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
June 2025 in “Albus Scientia” MC1R gene variations affect skin, hair color, UV sensitivity, and melanoma risk.
June 2025 in “Cell Regeneration” Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.
23 citations
,
March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
2 citations
,
September 2020 in “International journal of radiology & radiation therapy” Radiotherapy can cause rare changes in hair color, which should be discussed with patients.
94 citations
,
October 2017 in “International Journal of Dermatology” Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.
11 citations
,
August 1987 in “Archives of Dermatology” Langerhans' cells are not involved in hair depigmentation in these mice.
2 citations
,
September 2009 in “Pigment Cell & Melanoma Research” Melanocytes in different body areas have evolved to perform specific functions based on their location.
May 2020 in “International journal of biology, pharmacy and allied sciences” Vitiligo is often found with other autoimmune diseases, which is important to know to help patients.
December 1951 in “Journal of the American Medical Association” Propylthiouracil treatment can cause hair loss.
222 citations
,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
109 citations
,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
77 citations
,
August 1986 in “Archives of Dermatology” Vitamin B12 deficiency can cause skin and hair color changes, which are reversible with treatment.
58 citations
,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
47 citations
,
July 1967 in “Science” Not eating enough protein can cause hair roots to shrink and lose color, and hair to become thinner.
42 citations
,
March 2008 in “Molecular and Cellular Endocrinology” Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.
33 citations
,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
26 citations
,
February 2022 in “Journal of pineal research” Melatonin affects skin and hair color and protects skin cells, with potential benefits for hair growth and skin health.
23 citations
,
September 2018 in “Dermatologic Therapy” Microneedling is a safe and effective way to improve various skin conditions with minimal side effects.
20 citations
,
January 2003 in “Dermatology online journal” Prostaglandin analogs like Latanoprost might help grow hair on the scalp and body.
19 citations
,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.
19 citations
,
July 2004 in “Journal of Medical Primatology” Infant baboons suffered from zinc poisoning due to poor cage conditions.