research 869 The specification of Merkel cell in the back skin and glabrous paw skin is controlled by FGFR2-meditated signaling
FGFR2 signaling controls Merkel cell formation in different skin regions.
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390-420 / 1000+ resultsresearch Ectopic olfactory receptors in human: New therapeutic possibilities
Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.
research 647 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity in human melanoma
NLRP1 helps melanoma tumors grow by boosting inflammasome activation and reducing caspase-3 activity.
research 43367 Infantile Pacinian Neurofibroma: A Rare Neurogenic Tumor
A rare benign scalp tumor in an infant requires surgical removal.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Skin Hyperpigmentation in Complex Regional Pain Syndrome (CRPS) (P3.315)
Skin pigmentation increases in CRPS-affected areas and improves with symptom relief.
research Upregulation of genes orchestrating keratinocyte differentiation, including the novel marker gene ID2, by contact sensitizers in human bulge‐derived keratinocytes
The ID2 gene can help distinguish between sensitizers and irritants in skin cells.
research Expression of nerve growth factor in skin tissues and its effect on the proliferation of outer root sheath cells in cashmere goats
Nerve growth factor helps cashmere goat hair cells grow and is more active during the hair growth phase.
research 1377 Exploring the factors to regulate sweating by transcriptome analysis for anhidrosis: Novel role of olfactory receptors on sweating via exposing to β-ionone
Sweating can potentially be controlled through olfactory receptors, with β-ionone playing a key role, and responses may vary between genders.
research Hair Cycle Control by Vanilloid Receptor-1 (TRPV1): Evidence from TRPV1 Knockout Mice
TRPV1 helps regulate hair growth cycles.
research Finasteride, a 5alpha-reductase inhibitor, potentiates antinociceptive effects of morphine, prevents the development of morphine tolerance and attenuates abstinence behavior in the rat
Finasteride boosts morphine's pain relief and prevents tolerance and withdrawal in rats.
research Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis.
Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
research An Automatic AI‐Based Algorithm That Grades the Scalp Surface Exfoliating Process From Video Imaging. Application to Dandruff Severity and Its Validation on Subjects of Different Ages and Ethnicities
The AI device accurately grades scalp exfoliation and can help diagnose scalp disorders.
research The cellular basis of mechanosensory Merkel-cell innervation during development
BMP signaling is essential for the development of touch domes.
research Erythematous cutaneous nodules caused by adulterated cocaine
Talc in street cocaine can cause immune-reactive skin nodules where injected.
research GPCRs as key regulators in wound healing
GPCRs are vital for wound healing by affecting cell growth and immune response.
research 09-P004 Two populations of endochondral osteoblasts with differential sensitivity to Hedgehog signaling
research Melatonin Alleviates the Oxygen–Glucose Deprivation/Reperfusion-Induced Pyroptosis of HEI-OC1 Cells and Cochlear Hair Cells via MT-1,2/Nrf2 (NFE2L2)/ROS/NLRP3 Pathway
Melatonin may protect inner ear cells from damage by reducing cell death and oxidative stress, potentially treating sudden hearing loss.
research LB1009 Baicalin, a component of the herbal medicine Baikal skullcap, inhibits epidermal necroptosis in SJS/TEN
Baicalin may help treat severe drug-induced skin reactions.
research Chemotherapy-induced peripheral neuropathy: ice, compression, both, or neither?
Cryotherapy and compression therapy might help prevent chemotherapy nerve damage, but more research is needed.
research Novel Clove Essential Oil Nanoemulgel Tailored by Taguchi’s Model and Scaffold-Based Nanofibers: Phytopharmaceuticals with Promising Potential as Cyclooxygenase-2 Inhibitors in External Inflammation
Clove essential oil nanoemulgel effectively reduces skin inflammation and is a promising alternative to traditional anti-inflammatory drugs.
research [Transplanted epidermal neural crest stem cell in a peripheral nerve gap].
Epidermal neural crest stem cells from hair follicles can help repair nerve injuries.
research Pain relief and dermatological changes in complex regional pain syndrome with peripheral nerve stimulation
Peripheral nerve stimulation greatly reduced pain and improved skin symptoms in a CRPS patient.
research Comparative gene expression analysis of nestin-expressing hair follicle-derived cells
Nestin-expressing hair follicle cells may be useful for nerve repair and regeneration.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
research Author response: Hair follicle epidermal stem cells define a niche for tactile sensation
Skin stem cells in hair follicles are important for touch sensation.
research Author response: Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing
Reducing PIEZO1 speeds up wound healing.
research Increase in formalin-induced tonic pain by 5alpha-reductase and aromatase inhibition in female rats
Inhibiting certain enzymes made female rats more sensitive to low-level pain.
research The Effect of Local Skin Precooling on Alleviating Injection Site Pain in Patients With Androgenetic Alopecia Receiving a Scalp Nerve Block
Cooling the skin before injections reduces pain for patients with hair loss.
research Low-dose naltrexone: a novel adjunctive treatment in symptomatic alopecias?
Low-dose naltrexone might be a cheap and effective additional treatment for hair loss with scalp discomfort due to its anti-inflammatory effects and few side effects.