14 citations
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August 2021 in “Journal of Pharmaceutical Sciences” Cholesterol- and phospholipid-free niosomes improve deep skin drug delivery.
11 citations
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January 1977 in “Archives of dermatological research” Mouse tail skin has different keratinization near hair follicles and scales.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Neoplasms hide in hair follicles to avoid the immune system.
1 citations
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January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
54 citations
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September 1999 in “PubMed” K15 staining helps distinguish basal cell carcinoma from trichoepithelioma.
Fibronectin nanogel microneedles improve skin health and wound healing.
March 2021 in “Cell stem cell” Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
68 citations
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December 2011 in “Journal of Investigative Dermatology” Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
19 citations
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October 2022 in “The Ocular Surface” 44 citations
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January 2018 in “The International Journal of Developmental Biology” Stem cells in the skin help with healing and can also lead to cancer.
Hair germ cells differ from epidermal cells in keratin expression, and specific keratins form after hair differentiation.
A stable sheep ovarian cell line was created for studying reproduction and hormones.
23 citations
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June 1992 in “PubMed” RAR-gamma 1 is important for normal skin maintenance and differentiation.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Telocytes, cells with long extensions, are vital for hair growth because they produce Wnt signals, which are necessary for hair follicle regeneration.
2 citations
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September 2004 in “Experimental Dermatology” Desmosomal adhesion is essential for healthy skin structure and function.
52 citations
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February 1986 in “Journal of Histochemistry & Cytochemistry” Some hair proteins are specific to hair, while others are also found in skin cells.
1 citations
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December 1989 in “PubMed” Hair follicle cells can be grown without extra support and may help in wound healing.
417 citations
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September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
209 citations
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October 2018 in “Cell Reports” The study used single-cell transcriptomics to explore how Lgr5 and Lgr6 stem cells in mouse skin adapted during wound healing. It was found that Lgr5 progeny, initially in the hair follicle bulge, rapidly adapted to wound signals by adopting an interfollicular epidermis (IFE)-like signature within 1 day of wounding, allowing them to interact with the wound environment. In contrast, Lgr6 progeny, already in the IFE, were primed to respond to wound signals even before injury. The research highlighted the cellular plasticity of these stem cells and provided insights into their molecular adaptations during wound healing, emphasizing the importance of rapid transcriptional changes for effective wound repair. The study analyzed 1,873 cells, identifying 106 Lgr5TOM cells as potential wound cells, and revealed five distinct wound cell states.
192 citations
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March 2017 in “Cell host & microbe” Hair follicle development and microbes help regulatory T cells gather in newborn skin.
159 citations
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September 2018 in “Journal of Investigative Dermatology” Papillary and reticular fibroblasts have distinct roles and are influenced by their environment.
May 2020 in “International journal of dermatology and venereology” Hair matrix cysts are rare skin nodules with unique features, often needing surgical removal.
1010 citations
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August 2000 in “Cell” Hair follicle stem cells can form both hair follicles and skin.
32 citations
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February 2002 in “Veterinary Dermatology” Canine dermal papilla cells and fibroblasts have distinct growth patterns and protein expressions.
August 2021 in “Journal of Investigative Dermatology” ILC1-like cells can cause alopecia areata by disrupting hair follicle immunity, suggesting a new treatment approach.
Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.
37 citations
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January 2022 in “Frontiers in Genetics” Aging reduces dermal sheath cells, affecting youthful skin appearance.
7 citations
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March 1993 in “International Journal of Oncology” Basal cell carcinoma shows keratin patterns similar to hair follicle structures.
126 citations
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January 1987 in “Current topics in developmental biology/Current Topics in Developmental Biology” Different keratin proteins are expressed in various epithelial cells at different stages, affecting cell structure and function.
14 citations
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December 2007 in “Pediatric allergy and immunology” Newborns with the common rash Erythema Toxicum have many active mast cells in their skin, but these cells don't produce the LL-37 peptide.