13 citations
,
December 2012 in “Frontiers in bioscience” Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
January 2024 in “Skin appendage disorders” Oral finasteride seems more effective for hair loss in postmenopausal women, but more research is needed.
4 citations
,
October 2025 in “Journal of Cosmetic Dermatology” Unregulated exosome-based injections can cause severe skin reactions and scarring.
50 citations
,
December 2006 in “Bone” Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.
41 citations
,
February 2012 in “Journal of Neuroendocrinology” Allopregnanolone helps control oxytocin levels during pregnancy to prevent preterm labor.
July 2016 in “Reactions Weekly” Cyproterone and finasteride reduced hypersexuality but caused serious side effects.
12 citations
,
June 2022 in “FARMACIA” Transethosomal gels improve naftifine skin delivery better than Exoderil cream.
3 citations
,
September 2022 in “Journal of Drug Delivery Science and Technology” Minoxidil, a hair loss treatment, works better and has fewer side effects when put into tiny particles called transethosomes, especially those containing oleic acid.
1 citations
,
May 2015 in “Journal of The American Academy of Dermatology” Finasteride for hair loss in young men may significantly increase the risk of sexual dysfunction.
34 citations
,
April 2023 in “Climacteric” Gender-affirming hormone therapy affects health risks and requires careful management, especially as transgender individuals age.
5 citations
,
August 2014 in “Pharmaceutical Development and Technology” Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.
January 2016 in “The Korean Journal of Internal Medicine” Doxazosin may cause breast enlargement and pain in men.
84 citations
,
July 2008 in “Aaps Pharmscitech” Ethosomes improve finasteride delivery through skin for hair loss treatment.
6 citations
,
June 2000 in “Psychiatric Services” Maintaining sexual health after menopause is possible with patient approaches, hormone supplements, and therapy, despite needing more research.
179 citations
,
March 2005 in “British Journal of Dermatology” Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.
September 2024 in “International Journal of Molecular Sciences” High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.
January 2026 in “Updates in clinical dermatology”
2 citations
,
October 2015 in “Obstetrics and gynaecology cases - reviews” Removing both ovaries may better treat increased male hormone levels and related symptoms in postmenopausal women when hormone therapy doesn't work.
January 2007 in “Zhōnghuá yàoxué zázhì” The method effectively showed that the two exemestane preparations are bioequivalent.
August 2025 in “Journal of Cosmetic Dermatology” Oral minoxidil users, especially for hypertension, may risk heart issues, and better monitoring guidelines are needed for alopecia patients.
8 citations
,
March 2019 in “Drugs - Real World Outcomes” Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
16 citations
,
January 1998 in “Dermatology” Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.
research Acne
81 citations
,
January 2002 in “American journal of clinical dermatology” Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
13 citations
,
August 2013 in “Journal of pharmaceutical sciences” Researchers created a skin patch that delivers two drugs for treating enlarged prostate, which may improve patient use and dosage control.
November 2020 in “Elsevier eBooks” Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
38 citations
,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
5 citations
,
June 2018 in “Actas Dermo-Sifiliográficas” In 2017, Spanish dermatologists commonly prescribed topical minoxidil, oral finasteride, and nutricosmetics for hair loss, with oral contraceptives also used for premenopausal women. Less common were oral dutasteride, due to side effects, and newer, more expensive treatments like topical finasteride and Low-Level Laser Therapy. The conclusion is that there's a need for prescription guidelines due to varied treatment approaches.
31 citations
,
February 1982 in “Archives of dermatology” Etretinate was effective for certain skin conditions, but caused side effects like chapped lips, dry mucous membranes, and hair loss.
66 citations
,
October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.
12 citations
,
January 2020 in “Skin appendage disorders” Low-dose oral minoxidil effectively treats female hair loss with good safety.