research “MATH+” Multi-Modal Hospital Treatment Protocol for COVID-19 Infection: Clinical and Scientific Rationale
The MATH+ protocol aims to improve COVID-19 outcomes using a combination of specific treatments.
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150-180 / 1000+ results research Development of a new therapeutic approach based on peptide nanoparticles delivering CRISPR-Cas9 for the specific targeting of KRAS mutations
Peptide nanoparticles can effectively deliver CRISPR-Cas9 to target KRAS mutations in cancer.
research Characterization of factors that determine lentiviral vector tropism in skin tissue using an ex vivo model
Lentiviral vector effectiveness in skin is influenced by external factors, not receptor availability.
research Lentiviral Vector-Mediated Gene Transfer to Human Hair Follicles
research Targeted gene delivery to skin cells in vivo: A comparative study of liposomes and polymers as delivery vehicles
Nonionic liposomes are the best for delivering genes to skin cells.
research Efficient delivery of transgenes to human hair follicle progenitor cells using topical lipoplex
research Orders & Contracts
The method effectively delivers vaccines through the skin without needles.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research Particle-based transcutaneous administration of HIV-1 p24 protein to human skin explants and targeting of epidermal antigen presenting cells
This method is effective for needle-free HIV-1 vaccination by activating immune responses in the skin.
research In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
research Construction and Verification of Recombinant Follicle-specific Expression Vector
The vector successfully directed specific gene expression in hair follicles.
research Research Progress of Extracellular Vesicles-Loaded Microneedle Technology
Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
research Targeted delivery of siRNA to human cancer and human embryonic stem cells with cell level resolution
A new method using gold nanoshells and infrared light effectively delivers siRNA to cancer and stem cells with precision and minimal damage.
research [Experimental study on vascular endothelial growth factor 165 gene-modified rat hair follicle stem cells mediated by lentiviral vector].
Modified rat hair follicle stem cells can help create artificial hair follicles, blood vessels, and skin.
research Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
Bacterial extracellular vesicles could revolutionize regenerative medicine but need safety improvements.
research Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery
PLGA-based microneedles are promising for safe and effective skin delivery of drugs and vaccines.
research Application of Cell-Derived Extracellular Vesicles and Engineered Nanovesicles for Hair Growth: From Mechanisms to Therapeutics
Tiny natural vesicles from cells might help treat hair loss.
research Crosstalk between vimentin and keratins in viral infection: Implications across the viral life cycle
Vimentin and keratin help viruses spread and could be targets for antiviral treatments.
research Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks
Extracellular vesicles could offer precise treatments for psychiatric conditions by targeting brain networks.
research Exploiting Unique Features of Microneedles to Modulate Immunity
Microneedles offer a promising, painless, and efficient way to deliver vaccines and therapies directly to the skin.
research Gene Delivery to the Hair Follicle
Gene therapy shows promise for treating hair loss by targeting hair follicles.
research Detection of lentiviral constructs for release testing of CAR- T cells using digital droplet PCR
The new ddPCR method reliably detects unwanted viruses in CAR-T cell products, ensuring their safety for patients.
research Molecular mechanisms of viral oncogenesis in humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research Prophylactic Amotosalen-Treated Donor T-Cells Prevent Late CMV Infection in Allogeneic Bone Marrow Transplantation.
Amotosalen-treated donor T-cells can prevent late CMV infection after bone marrow transplants.
research Engineered extracellular vesicles for tissue repair and regeneration
Engineered extracellular vesicles can improve tissue repair and regeneration.
research New intranasal and injectable gene therapy for healthy life extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research NEW GENERATION OF VACCINE TECHNOLOGIES
New vaccine technologies are improving global health by making vaccines more effective and long-lasting.
research The role of 3Rs in the age of One Health: where we are and where we’re going
Innovative methods are reducing animal testing and improving biomedical research.
research Bio-Nanovesicle-Based Approaches for Hair and Skin Regeneration: An Updated Concise Review
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.