171 citations
,
July 2007 in “Journal of Investigative Dermatology” A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
107 citations
,
December 2013 in “International Journal of Dermatology” The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.
45 citations
,
January 2012 in “Experimental Dermatology” Human hair follicles switch between active and resting phases unpredictably.
34 citations
,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
32 citations
,
August 2015 in “Journal of Investigative Dermatology” Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
30 citations
,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
18 citations
,
May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
13 citations
,
December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.
11 citations
,
October 2001 in “Tissue engineering” Cultured epithelium can form hair follicles when combined with dermal papillae.
8 citations
,
January 2013 in “The scientific world journal/TheScientificWorldjournal” Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
1 citations
,
October 2001 in “Journal of Wood Science” Some extracts from woods and fungi can promote hair growth better than a known hair growth substance.
June 2024 in “Georgetown Scientific Research Journal” Bleomycin injections in mice cause skin thickening and hair loss.
July 2023 in “Indian Journal of Animal Health” FGF-5 promotes Cashmere goat hair growth by increasing keratin genes and reducing certain LncRNA and target genes.
January 2021 in “Journal of clinical and cosmetic dermatology” Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
February 2009 in “Journal of The American Academy of Dermatology” Fractional infrared technology is effective and safe for treating cervical laxity.
57 citations
,
July 2018 in “Scientific Reports” Using adipose tissue-derived fragments improves early skin graft success.
23 citations
,
June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
4 citations
,
August 2011 in “Aktuelle Dermatologie” Topical melatonin is a safe treatment that may reduce hair loss in people with androgenetic alopecia.
19 citations
,
November 2012 in “British Journal of Dermatology” Dopamine stops hair growth and pigment production in human scalp hair follicles.
301 citations
,
February 2019 in “Nature Communications” The research found that different types of fibroblasts are involved in wound healing and that some blood cells can turn into fat cells during this process.
276 citations
,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
48 citations
,
May 2015 in “NPJ microgravity” A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
46 citations
,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
35 citations
,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
33 citations
,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
17 citations
,
May 2015 in “Nanomedicine: Nanotechnology, Biology and Medicine” Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.
14 citations
,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
13 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Researchers created a lab model to study human hair growth, showing it can grow and self-regulate outside the body.
9 citations
,
August 2017 in “Photochemistry and Photobiology” Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
6 citations
,
October 2018 in “Bioelectromagnetics” Rice bran extract and low-frequency electromagnetic fields together may help treat vitiligo and white hair.