18 citations
,
January 1996 in “Gynecologic and obstetric investigation” The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
22 citations
,
November 2018 in “Breast Cancer Research and Treatment” The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.
9 citations
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June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
4 citations
,
June 2003 in “Fertility and Sterility” Finasteride doesn't affect ovulation in normal women.
34 citations
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March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
2 citations
,
June 2022 in “Scientific reports” Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
11 citations
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July 2015 in “Gene” DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
Use mild topical steroids to avoid side effects, especially in children.
15 citations
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June 2019 in “Biochemical Journal” A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
30 citations
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January 2001 in “Journal of the American Veterinary Medical Association” High adrenal sex hormones in dogs with hypercortisolemia can mislead adrenal hyperplasia diagnosis.
1 citations
,
January 2005 in “PubMed” Steroids affect skin health and healing, offering new treatment options.
30 citations
,
December 2001 in “Journal of The European Academy of Dermatology and Venereology” Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
November 2024 in “Skin Appendage Disorders” Start low-dose minoxidil gradually, especially for women, to reduce side effects.
44 citations
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February 2009 in “Pain” Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
80 citations
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August 1991 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
1 citations
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August 2024 in “GeroScience”
2 citations
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October 2001 in “Analytical Sciences” A new compound that could treat various androgen-related conditions was created and analyzed.
90 citations
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December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
December 2025 in “Pakistan Journal of Health Sciences” Estrogen deficiency in postmenopausal women can cause skin and hair issues, but local estrogen therapies help improve vaginal health.
January 2016 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” CAP7.1 is generally safe at 200 mg/m²/day, but can cause fatigue, nausea, hair loss, fever, and blood-related issues.
May 2021 in “Journal of the Endocrine Society” Long-term opioid use can cause a serious condition where the adrenal glands don't work properly, which doctors should watch out for.
1 citations
,
September 2013 in “Annales d Endocrinologie” Hirsutism often links to polycystic ovary syndrome and high testosterone, needing thorough investigation.
63 citations
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February 2013 in “Human cell” PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.
7 citations
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January 2014 in “Case reports in endocrinology” A woman's excessive hair growth was caused by a rare benign tumor in her adrenal gland, which was successfully removed.
1 citations
,
November 2009 in “Gynäkologische Endokrinologie”
May 2024 in “International Journal of Advanced Academic Studies” Vitamin E helps reduce PCOS symptoms and improves hormonal balance.
23 citations
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January 2016 in “Transgender health” Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
32 citations
,
January 1990 in “Clinical Endocrinology” Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.
27 citations
,
May 1976 in “PubMed” Ovarian wedge resection helped regulate menstrual cycles but didn't significantly change hormone levels or hair growth in polycystic ovary syndrome.
120 citations
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October 2007 in “Clinical Interventions in Aging” Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.