research Opinions and expectations of psoriasis-affected people regarding substances derived from Cannabis sativa
People with psoriasis are using cannabis products for skin care but need more reliable information and education.
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960-990 / 1000+ results research Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice
Progesterone's seizure-reducing effects are mainly due to allopregnanolone, not progesterone receptors.
research Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depression
Depressed teens have different steroid levels in urine, which may help identify and treat them.
research Antidiabetic Management Strategies for Treatment of Polycystic Ovarian Syndrome
Combining antidiabetic drugs, hormonal therapies, and lifestyle changes can improve health in women with PCOS.
research Oak bark extract/salicylic acid/benzoic acid ointment attenuates the inflammatory response in a murine model of hair shaving associated dermatitis
research The TRPM5 Antagonist Triphenylphosphine Oxide Increases Sebaceous Lipogenesis and Modulates Immune Phenotype of Human Sebocytes in a TRPM5‐Independent Manner
Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.
research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights
Compound 7p shows strong potential as an anticancer agent.
research Advancements in transdermal drug delivery using microneedles: technological and material perspective
Microneedle patches offer painless, effective drug delivery and are suitable for all ages.
research Persistent escalation of alcohol consumption by mice exposed to brief episodes of social defeat stress: suppression by CRF-R1 antagonism
Blocking CRF-R1 can reduce alcohol intake in stressed mice.
research Visual Vignette
The woman's symptoms and tests suggest her adrenal glands are producing too many male hormones.
research Anti-Androgen Drugs in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review
Anti-androgen drugs can help reduce OCD symptoms, but more large-scale trials are needed to confirm their effectiveness.
research INDUCTION OF PSORIASIFORM CHANGES IN GUINEA PIG SKIN BY PROPRANOLOL
Propranolol combined with injections caused skin changes in guinea pigs but didn't fully mimic psoriasis.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research 196 The endocannabinoid tone regulates human sebocyte biology
The endocannabinoid system affects oil production and inflammation in skin cells.
research Signaling pathways in the mechanisms of drug action
Signaling pathways are key targets for developing effective drugs.
research Therapeutic Effects of Patchouli (Pogostemon cablin) Essential Oil in Relieving Eczema Symptoms in Infants and Toddlers: A Literature Review
Patchouli essential oil may help reduce eczema symptoms in infants and toddlers.
research Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial
Melatonin improved mental health and metabolism in women with PCOS.
research Rapid hair depigmentation in patient treated with pazopanib
Pazopanib treatment caused rapid hair color loss, possibly indicating its effectiveness.
research Hirsutism, Male Pattern Baldness, and Acne in a 60-Year-Old Woman
Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.
research Anabolic potential of bone mineral in human periosteal fibroblasts using steroid markers of healing
Bone mineral and minocycline boost bone cell growth, aiding healing.
research Possible Role of Osteopathic Manipulation Treatment in Alleviation of Finasteride-Induced Dementia through Modulation of HOMER-3 Gene Methylation
Osteopathic manipulation therapy might help treat dementia caused by finasteride.
research Effective treatment of skin and metabolic manifestations of hyperandrogenism: a comprehensive improvement of quality of life
Combined oral contraceptives improve skin, hormone levels, and quality of life in women with PCOS.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Role of Matra basti in polycystic ovary syndrome
Ayurvedic treatment, including Matra basti, may help improve PCOS symptoms.
research Ultrasound-Assisted Facile Synthesis and Anticancer Evaluation of Novel N-(2-substituted phenyl-4-oxathiazolidine-3-carbonothioyl) benzamide
Researchers made new compounds that could potentially be developed into anticancer drugs.
research Sodium valproate
Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.
research Can we teach old drugs new tricks?—Repurposing of neuropharmacological drugs for inflammatory skin diseases
Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Hormonal Therapy for Acne
Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
research Hyperandrogenemia in an ethnically heterogeneous cohort of Midwestern United States diabetic gestations
Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.