January 2024 in “Archives of pharmacy practice” The skin is vital for protection, temperature control, fluid balance, immunity, and sensing, with damage affecting daily life and mental health.
January 2011 in “Hispania Judaica bulletin” Mechanical forces are crucial for hair regeneration in skin organoids.
4 citations
,
October 2004 in “Humana Press eBooks” Epidermal growth factor stops hair follicle formation in developing mouse skin.
7 citations
,
January 2019 in “Methods in molecular biology” Engineered skin with hair follicles can improve burn treatments.
26 citations
,
December 2013 in “Seminars in cell & developmental biology” Skin varies in thickness, color, and features due to complex genetic and cellular processes.
28 citations
,
November 1987 in “Journal of the American Academy of Dermatology” The model successfully grew and differentiated hair follicle cells in the lab.
August 1993 in “Journal of Dermatological Science” July 2025 in “Journal of Investigative Dermatology” Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.
44 citations
,
November 2014 in “Tissue Engineering Part C Methods” Porcine skin varies by region, affecting its use as a human skin model.
18 citations
,
September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
April 2026 in “Experimental & Molecular Medicine” Mouse and human skin development share similar fibroblast timelines.
9 citations
,
January 1990 in “Skin Pharmacology and Physiology” The method and source of keratinocytes affect the structure of reconstructed skin.
October 2021 in “Journal of Investigative Dermatology” The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
The new biomimetic skin heals wounds faster and better than traditional treatments, without scarring.
A comprehensive human skin cell atlas was created to better understand skin biology and disease.
4 citations
,
June 2007 in “PubMed” Engineered skin with specific cells can effectively repair skin and restore its function.
New bio-ink can print complex tissues and organs.
12 citations
,
September 2020 in “Stem cell research & therapy” Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.
50 citations
,
April 2014 in “Nature Communications” The research identified new skin traits in mice, some linked to human skin conditions.
January 2019 in “Data Archiving and Networked Services (DANS)” Current skin substitutes don't fully replicate natural skin, and better understanding of molecular mechanisms is needed for improvement.
A new imaging method helps see and study touch nerve endings in mouse skin.
1 citations
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November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
September 2017 in “Journal of Investigative Dermatology” Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
5 citations
,
January 2021 in “Wiadomości Lekarskie” The method effectively creates acellular dermal matrix from pig skin while preserving structure.
January 2011 in “Journal of Tissue Engineering and Reconstructive Surgery” Using dermal papillae cells and keratinocytes in skin substitutes speeds up healing and helps form hair follicles and glands.
Hair bulb cells can create skin-like tissues for potential skin repair.
6 citations
,
April 2001 in “The Anatomical Record” A new method using hair pores can help align skin grafts better, improving results.
August 2022 in “Tissue Engineering Part A” Advancements in skin treatment and wound healing include promising gene therapy, 3D skin models, and potential new therapies.