research Ultrastructural Localization of Hair Keratins in Human Scalp Hair Shafts as Revealed by Rapid-Freezing Immunocytochemistry.
Hair keratins are mainly on macrofibrils in the cortex and in the endocuticle in the cuticle.
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research Reviewer #1 (Public Review): Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis
Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
research Sequences and differential expression of three novel human type-II hair keratins
Hair differentiation starts earlier than thought, involving multiple type-II keratins.
research Hierarchical patterning modes orchestrate hair follicle morphogenesis
Hair follicle patterns form through a mix of self-organization and signaling interactions.
research Striae distensae over scalp: a trichoscopic revelation
Trichoscopy can detect early signs of steroid overuse on the scalp, suggesting a need for non-steroidal treatments.
research Onychomatricoma in the Light of the Microanatomy of the Normal Nail Unit
Onychomatricoma is a unique nail tumor that mimics the entire nail unit and is not related to other hair-related tumors.
research X-rays studies of the structure of hair, wool, and related fibres. II. - The molecular structure and elastic properties of hair keratin
Stretched hair has a similar structure to natural silk, showing hair's elasticity involves reversible changes within its molecules.
research Carbon-13 n.m.r. studies of keratin intermediate filament of human hair
Human hair keratin has a 40% α-helix structure that changes to a random coil in 8 M urea.
research Generating Skin‐Derived Precursor‐Like Cells From Human‐Induced Pluripotent Stem Cell‐Derived Skin Organoids
SKO-derived SKP-like cells may help with hair regeneration and skin restoration.
research Immunohistochemical analysis of tissue remodelling during the anagen-catagen transition of the human hair follicle
The inner root sheath is crucial for hair follicle stability during the transition from growth to involution.
research Hairless Descendants of Mexican Hairless Dogs: An Experimental Model for Studying Hypertrophic Scars
Hairless dogs can be used to study human hypertrophic scars.
research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes
Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
research Clinical and Dermoscopic Correlation in Secondary Syphilis: A Report of Three Cases
Dermoscopy can help diagnose secondary syphilis by distinguishing it from other skin issues.
research A modified Sobel filter-based automated numerical algorithm enables immediate trichoscopic assessment of hair diameter diversity in male and female pattern hair loss
A new computer tool quickly measures hair thickness differences in people with common types of hair loss.
research Genomic and anatomical comparisons of skin support independent adaptation to life in water by cetaceans and hippos
research The New Keratin Nomenclature
The keratin naming system was updated to include 54 genes, especially for hair-related keratins.
research Queratose folicular espinulosa decalvante: relato de caso
A rare genetic disease caused severe, worsening hair loss from early childhood with poor treatment results.
research Syphilitic Alopecia Through the Dermoscope: A Series of two Cases
Dermoscopy is useful for accurately diagnosing syphilitic alopecia.
research Three cases of immune‐mediated adnexal skin disease treated with cyclosporin
Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.
research Histopathological and Ultrastructural Study of Ectodermal Dysplasia/Skin Fragility Syndrome
The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.
research Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs
A PKP1 gene mutation causes skin fragility and hair loss in Chesapeake Bay retriever puppies.
research Graham Little-Piccardi-Lassueur syndrome associated with androgen insensitivity syndrome (testicular feminization)
A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.
research Dermal Mass Aspirate from a Persian Cat
The Persian cat has a skin infection caused by a fungus, treatable with antifungal medication.
research Targeted therapy in melanoma
New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.
research Systemic effects of Leucaena leucocephala ingestion on ringtailed lemurs (Lemur catta) at Berenty Reserve, Madagascar
Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.
research Concurrent follicular dysplasia and interface dermatitis in Boxer dogs
Boxer dogs may have a genetic skin condition that worsens seasonally and can be treated with certain medications.
research Adult‐onset hair loss in Chesapeake Bay retrievers: a clinical and histological study
Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.
research Dermatologic Diseases
The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.
research Canine cutaneous epitheliotropic T-cell lymphoma with vesiculobullous lesions resembling human bullous mycosis fungoides
Vesiculobullous lesions should be considered part of canine cutaneous epitheliotropic T-cell lymphoma.
research Mast Cells and Scarring Alopecia: Is There a Clear Pathophysiological Relationship?
The document suggests a possible link between mast cells and scarring alopecia, recommending more research for potential treatments.