222 citations
,
August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
January 2018 in “Contributions to management science” MicroRNAs are crucial for skin development, regeneration, and disease treatment.
101 citations
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December 2014 in “Stem Cells and Cloning Advances and Applications” Oral stem cells show promise for tissue repair, but more human trials are needed.
78 citations
,
October 2007 in “Journal of Investigative Dermatology” Delta1 is crucial for controlling skin cell growth and preventing tumors in mice.
65 citations
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November 2013 in “The EMBO Journal” HDAC1 is crucial for skin development and preventing tumors.
47 citations
,
August 2016 in “American Journal Of Pathology” Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
39 citations
,
September 2007 in “BMC developmental biology” Neuregulin3 affects cell development in the skin and mammary glands.
32 citations
,
December 2019 in “The Journal of clinical investigation/The journal of clinical investigation” A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.
22 citations
,
December 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” A mouse gene mutation increases the risk of skin cancer.
20 citations
,
November 2014 in “Developmental Dynamics” Palate formation and skin healing share similar biological processes.
18 citations
,
August 2015 in “International Journal of Molecular Sciences” Ovine hair follicle stem cells can regenerate haired skin and may improve wool production.
17 citations
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October 2023 in “Molecules” Plant-derived PDRN from ginseng roots effectively heals skin and improves its barrier.
16 citations
,
January 2021 in “BMC Genomics” Higher hair follicle density leads to more wool in rabbits, influenced by specific genes and lncRNAs.
10 citations
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August 2021 in “Frontiers in cell and developmental biology” Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.
9 citations
,
May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
5 citations
,
June 2024 in “Free Radical Biology and Medicine” Maintaining natural oxygen levels is crucial for healthy skin cells and effective treatments.
3 citations
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January 2023 in “Science advances” The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
3 citations
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January 2023 in “International journal of molecular sciences” Certain miRNAs play a key role in the growth of cashmere by affecting hair follicle development and regeneration.
3 citations
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March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
1 citations
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July 2023 in “Communications biology” Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
1 citations
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May 2022 in “International journal of molecular sciences” Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.
1 citations
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February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” Certain cancer drugs interact with skin bacteria to cause acne-like rashes.
July 2025 in “Biotechnology and Bioprocess Engineering” Camellia japonica seed extract helps hair grow by activating hair follicles and preventing cell aging.
February 2025 in “Stem Cell Research & Therapy” Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
January 2025 in “PLoS ONE” Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.
August 2022 in “Biomedicines” Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.
3 citations
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August 2020 in “Nutrition Journal” Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.
12 citations
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January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.