2 citations
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August 2019 in “BMC Complementary and Alternative Medicine” Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
April 2017 in “Journal of Investigative Dermatology” Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
January 2015 in “DSpace@MIT (Massachusetts Institute of Technology)” PHGDH promotes cancer growth by aiding cell proliferation and tumor progression.
3 citations
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February 2018 in “Experimental and Molecular Medicine/Experimental and molecular medicine” A protein called PCBP2 controls the production of a hair growth protein by interacting with its genetic message and is linked to hair loss when this control is disrupted.
17 citations
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February 2018 in “Journal of Investigative Dermatology” PPAR-γ signaling improves mitochondrial function in hair follicles, potentially affecting hair growth and aging.
DNA methylation affects BMP7 gene expression, influencing cell growth in Hu sheep.
24 citations
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January 2003 in “Journal of Investigative Dermatology” Blocking a specific receptor slows down hair loss in mice.
38 citations
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July 2019 in “Nature Communications” Par3 protein is essential for skin cell balance and stability.
12 citations
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May 2003 in “Journal of dermatological science” Hsc70 protein may influence hair growth by responding to androgens.
October 2025 in “Cell Death and Disease” CD271 is crucial for maintaining healthy skin and preventing inflammation.
4 citations
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February 2018 in “Journal of Investigative Dermatology” The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.
16 citations
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May 2000 in “Endocrinology” A new gene, mrp4, is found in mice and may play a unique role in hair follicle development in tails and ears.
April 2016 in “Journal of Investigative Dermatology” Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.
August 2005 in “The Journal of Cell Biology” Sgk3 kinase is essential for normal hair growth in mice.
79 citations
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October 2003 in “PubMed” Overexpression of PKCepsilon leads to increased TNFalpha, promoting metastatic squamous cell carcinoma in mice.
9 citations
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February 2001 in “Journal of Dermatological Science” p21waf1/cip1 and p27kip1 help in hair follicle differentiation in rats.
106 citations
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October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
1 citations
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December 2022 in “Archives of Dermatological Research” Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
48 citations
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April 2008 in “Human Molecular Genetics” Progerin affects cell shape but not hair or skin in mice.
3 citations
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June 2017 in “Journal of Physiology & Pathology in Korean Medicine” Puerariae Radix extract may help hair growth by increasing cell activity.
December 2022 in “Research Square (Research Square)” Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
May 2022 in “Research Square (Research Square)” Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
April 2023 in “Journal of Investigative Dermatology” A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.
April 2023 in “Journal of Investigative Dermatology” POUF51 and HES3 are key in controlling stem cell numbers in psoriasis.
12 citations
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November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
19 citations
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September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.
51 citations
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September 2000 in “Acta dermato-venereologica” PPAR alpha may help in hair growth and could be a target for treatment.