4 citations
,
January 2024 in “Allergy” Everyone has an immune response to PPD, but reactions differ, causing tolerance, mild inflammation, or allergy.
March 2026 in “Indian Dermatology Online Journal” Hair dye ingredient PPD can cause severe allergic reactions, including facial swelling.
20 citations
,
June 2011 in “ISRN Dermatology (Print)” A woman lost most of her hair due to an allergic reaction to a hair dye ingredient.
9 citations
,
July 2012 in “Dermatitis” Hair dye with para-phenylenediamine can cause skin depigmentation.
8 citations
,
March 2015 in “Molecular Medicine Reports” Hair dye ingredient PPD causes cell death and aging in human hair cells by altering microRNA levels.
6 citations
,
January 2016 in “Indian Journal of Dermatology Venereology and Leprology” Most hair dyes can cause allergic reactions, so test before use.
1 citations
,
October 2025 in “Iranian journal of pharmaceutical research” Geranyl acetate can protect skin cells from damage and inflammation caused by para-phenylenediamine.
79 citations
,
January 1975 in “Food and Cosmetics Toxicology” The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
63 citations
,
February 2017 in “ACS biomaterials science & engineering” Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
47 citations
,
June 2015 in “Contact Dermatitis” A standardized patch test for hair cosmetics is needed in Europe to prevent allergies, especially for hairdressers.
40 citations
,
February 2002 in “International Journal of Dermatology” Permanent hair dye damages hair but it mostly recovers after 8 weeks; using certain hair care products can help repair it.
33 citations
,
April 2020 in “Dermatitis” Hair care products often cause contact dermatitis, especially in women and hairdressers.
12 citations
,
December 2017 in “Food and chemical toxicology” Permanent hair dye mixtures can irritate and damage the skin.
6 citations
,
January 2020 in “Elsevier eBooks” Nanoparticles could make hair dyes safer by reducing harmful effects.
5 citations
,
July 2022 in “PubMed” Hair dyes, shampoos, and conditioners often cause scalp allergies due to common allergens like p-phenylenediamine and nickel.
5 citations
,
February 2019 in “Journal of oceanology and limnology (Online)” Ecklonia cava extract can reduce the damage and stress caused by hair dye.
November 2025 in “International Journal of Biological Macromolecules” This eco-friendly hair dye method improves hair health and color durability.
June 2023 in “Italian journal of dermatology and venereology” Trichoscopy effectively diagnoses allergic scalp contact dermatitis.
8 citations
,
September 2004 in “Contact dermatitis” Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
1 citations
,
March 2022 in “Journal of burn care & research” Eyebrow tinting can cause chemical burns and increased awareness of its risks is needed.
43 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The article concludes that advancements in hair cosmetics require dermatologists to stay informed about products and their potential risks, including allergies and higher risks for hairdressers.
16 citations
,
October 2009 in “Xenobiotica” The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
1 citations
,
July 2016 in “Cosmetics” Black henna tattoos can cause severe allergies to hair and textile dyes, and there's a need for greater public awareness and regulation.
November 2024 in “Dermatitis” Men's personal care products often cause allergic skin reactions.
98 citations
,
November 2002 in “Contact Dermatitis” Many people had severe allergic reactions to a common hair dye ingredient, causing them to seek medical care and miss work.
March 2007 in “The FASEB Journal” Henna mixed with PPD can cause skin reactions, scarring, and a specific type of baldness, and needs more research to understand these effects.
February 2026 in “Indian Journal of Dermatology” Adults are more reactive to allergens than older adults, who are more sensitive to medication-related allergens.
August 2022 in “Zenodo (CERN European Organization for Nuclear Research)” The herbal hair dye effectively provides a natural reddish-brown color without synthetic chemicals.
18 citations
,
January 2016 in “Skin appendage disorders” The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
December 2020 in “International journal of research in ayurveda and pharmacy” Eating well and avoiding synthetic hair products are key for healthy hair.