January 2013 in “搏击:体育论坛” Curcumin shows promise for pain relief but needs more research for effective use.
January 2011 in “Journal of The American Academy of Dermatology” A man developed a painful skin condition after multiple heart procedures involving radiation.
April 2009 in “Journal of Pain” Finasteride reduces pain in male rats and works better with testosterone.
A man with painful ear plaques was diagnosed with discoid lupus and treated with medications and lifestyle changes.
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” Microneedles offer a painless way to deliver drugs effectively but need more research before they can be widely used.
Pseudofolliculitis causes painful bumps and dark spots from shaving, especially in people with curly hair, and can be treated by changing shaving habits and using specific topical treatments.
January 2012 in “Open MIND” Oral minoxidil can cause painful skin bumps and scarring in some people.
46 citations
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January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
42 citations
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January 2021 in “Journal of Clinical Medicine” Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
41 citations
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December 2015 in “JAMA Dermatology” Tofacitinib citrate improved nail dystrophy and pain in patients with alopecia universalis without causing side effects.
26 citations
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April 2006 in “Cephalalgia” Botulinum A toxin injections reduced pain and promoted hair regrowth in a woman with a rare form of alopecia areata.
24 citations
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September 2020 in “Pharmaceutics” Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
22 citations
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November 2023 in “Molecules” Smart microneedles can deliver drugs painlessly and accurately for diseases like diabetes and tumors.
17 citations
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January 2023 in “Frontiers in Pharmacology” 2Br-Crebanine and Stephanine reduce inflammation and pain effectively.
16 citations
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July 2000 in “Dermatologic surgery” The multi-injection plate is a less painful and more efficient method for treating patchy hair loss.
16 citations
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April 2017 in “Pediatric Dermatology” Oral isotretinoin effectively treated the man's painful scalp condition and hair loss.
15 citations
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May 2013 in “Ophthalmic Plastic and Reconstructive Surgery” Botulinum toxin injections greatly reduced pain in Parry-Romberg syndrome.
8 citations
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January 2014 in “Journal of Stem Cell Research & Therapy” Stem cell therapy improves healing and reduces pain in cutaneous radiation syndrome.
6 citations
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March 2024 in “Saudi Pharmaceutical Journal” The new delivery system could improve pain and inflammation relief in gout.
6 citations
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July 2023 in “Spine Surgery and Related Research” PRP shows promise for spinal pain but needs more guidelines before widespread use.
6 citations
,
September 2010 in “Archives of Dermatology” Thermography matched the patient's pain levels in a shingles case and might help diagnose shingles without a rash.
6 citations
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February 2010 in “Journal of The American Academy of Dermatology” A woman had a rare skin condition with recurring painful nodules that heal in 6 weeks, often without needing treatment.
5 citations
,
January 2020 in “Research journal of pharmacy and technology” CBD may help reduce stress and pain in women with PCOS.
3 citations
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November 2019 in “Journal of dermatology” Itraconazole effectively treated a woman's painful skin condition and hair loss.
3 citations
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January 2019 in “Česká a slovenská farmacie” Microneedles could make it easier and less painful to deliver more types of drugs through the skin.
2 citations
,
January 2025 in “Annals of Maxillofacial Surgery” Low-level laser therapy reduces pain, swelling, and improves healing after wisdom tooth removal.
2 citations
,
April 2024 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” Women with PCOS have more frequent menstrual pain, but the pain's intensity is similar to those without PCOS.
2 citations
,
April 2022 in “PLoS ONE” Vibration treatment may reduce migraine pain by changing cell structures.
2 citations
,
February 2020 in “Rivista Urologia” Both terazosin and baclofen effectively reduce pain in young men with chronic testicular pain, with no difference in their effectiveness.
2 citations
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July 2019 in “International Journal of Neuroscience and Behavioral Science” Thevetia peruviana bark extract reduces pain in mice and may help create new painkillers.