222 citations
,
September 2016 in “JCI insight” Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.
205 citations
,
April 2013 in “British Journal of Dermatology” Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.
34 citations
,
February 2012 in “Journal of Cutaneous Pathology” The research found specific signs to diagnose alopecia areata incognito and noted patients generally regrow hair after steroid treatment.
20 citations
,
December 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.
3 citations
,
April 2019 in “Journal of Dermatological Treatment” Caffeine shows promise for treating some types of hair loss, but more research is needed.
3 citations
,
February 2014 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Herbal medicine and acupuncture helped regrow hair and reduce pain in a patient with Alopecia Areata.
1 citations
,
January 2024 in “Annals of Dermatology” Examining hair shape can help predict Alopecia Areata's progression.
September 2025 in “Journal of Dhaka Medical College” Lower vitamin D levels are linked to more severe alopecia areata.
October 2021 in “Dermatology Reports” Higher IL-17A levels indicate more severe alopecia areata.
18 citations
,
January 2017 in “Annals of dermatology/Annals of Dermatology” Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
3 citations
,
January 2023 in “Dermatology Practical & Conceptual” IMA and IMA/albumin levels don't predict alopecia areata severity.
188 citations
,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
133 citations
,
July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
107 citations
,
April 2014 in “The Plant cell” The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.
86 citations
,
August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
73 citations
,
January 2013 in “Annals of Dermatology” People with hair loss, especially those with certain types, have lower zinc levels, and zinc supplements might help.
62 citations
,
June 2015 in “The Journal of Dermatology” People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.
58 citations
,
January 2018 in “International Journal of Women's Dermatology” Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.
54 citations
,
September 2019 in “Journal of the European Academy of Dermatology and Venereology” Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.
51 citations
,
January 2012 in “Annals of dermatology/Annals of Dermatology” A boy with alopecia regrew hair using a vitamin D cream after other treatments failed.
42 citations
,
July 2010 in “International Journal of Dermatology” Dermatoscopy and videodermatoscopy are useful and reliable for tracking treatment progress in various skin conditions.
40 citations
,
January 2022 in “Frontiers in Chemistry” The patch speeds up deep wound healing.
34 citations
,
January 1987 in “Dermatology” Topical minoxidil effectively and safely treats extensive alopecia areata but doesn't change its course.
31 citations
,
October 2010 in “Journal of the European Academy of Dermatology and Venereology” Some people with heavy hair shedding might actually have a hidden form of alopecia, which can be identified by specific hair changes.
29 citations
,
September 2012 in “Dermatologic Clinics” Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.
28 citations
,
January 2011 in “Hearing Research” Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
23 citations
,
October 2005 in “Journal of The American Academy of Dermatology” Two transplant patients on cyclosporine unexpectedly developed hair loss.
21 citations
,
January 2023 in “Biomaterials Science” Microneedle patches with alpha-arbutin and resveratrol can effectively reduce skin pigmentation without irritation.
20 citations
,
January 2012 in “International journal of trichology” Steroids are the best treatment for Alopecia Areata with few side effects.
20 citations
,
December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.