research Diabetes mellitus: interdisciplinary medical, surgical and psychological therapeutic approach
A holistic approach combining medical, surgical, and psychological therapies is essential for effectively managing diabetes.
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240-270 / 1000+ resultsresearch Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors
14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
research Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models.
Feather patterns form through genetic and epigenetic controls, with cells self-organizing into periodic patterns.
research Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1
A fungal enzyme was used to make compounds more soluble, aiding drug discovery and crop protection.
research Inorganic Nanomaterial for Biomedical Imaging of Brain Diseases
Inorganic nanomaterials can improve brain disease imaging by being more precise and faster than traditional methods.
research Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation
Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
research Molecular docking simulation studies on potent butyrylcholinesterase inhibitors obtained from microbial transformation of dihydrotestosterone
Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
research Advances and Perspectives on Bioelectronic and Atomic Nanogenerators for Anticancer Therapy
Bioelectronic nanogenerators show promise for cancer treatment but need better understanding and development.
research Clinical Applications of Extracellular Vesicles: Promises and Pitfalls
Extracellular vesicles show promise for medical use but face challenges in standardization and safety.
research Development and Evaluation of Nanoemulgel Loaded with Minoxidil
The new minoxidil nanoemulgel may treat hair loss more effectively with fewer side effects.
research Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum japonicum : Glycosylation of Methyl Gallate with Ulosyl Bromides
Researchers created 10 new compounds similar to cercidin, which could lead to new antibiotics.
research Signal integrator function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Bleached Hair as Standard Template to Insight the Performance of Commercial Hair Repair Products
K18® and Olaplex® both effectively repair bleached hair, improving its strength, smoothness, and overall health.
research The Potential of Ginkgo biloba as a Source of Biologically Active Compounds—A Review of the Recent Literature and Patents
Ginkgo biloba has health benefits but also contains toxic compounds, driving interest in its use in medicine and food.
research Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications
Seaweeds contain beneficial compounds with potential uses in food, cosmetics, and health, but more research is needed to improve extraction and safety.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Identification of hepatic molecular mechanisms of action of alpha-tocopherol using global gene expression profile analysis in rats
Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
research Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation
MMP-19 may worsen skin diseases by affecting skin growth and inflammation.
research Genome-Wide Association Study for Udder Conformation Traits in Chinese Holstein Cattle
Certain genes affect udder shape in Holstein cows, important for health and milk production.
research Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024
In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
research Bioarchitectural Design of Bioactive Biopolymers: Structure–Function Paradigm for Diabetic Wound Healing
Bioactive biopolymers can improve diabetic wound healing by enhancing tissue regeneration.
research Applications of Antioxidant Nanoparticles in Immune-Mediated Inflammatory Diseases
Antioxidant nanoparticles show promise for treating inflammatory diseases but need more research for safe and effective use.
research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines
The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.
research Medicinal Chemistry of Drugs with N-Oxide Functionalities
N-oxides are important in medicine for improving drug properties and targeting.
research Advances in Chitosan-Based Nanoparticles for Drug Delivery
Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
research Drug repurposing: Clinical practices and regulatory pathways
Drug repurposing offers faster, cheaper drug development but faces challenges like safety, ethics, and funding.
research Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process
Nanoparticles can effectively treat diseases by modifying blood vessel growth.
research JAK inhibition decreases the autoimmune burden in Down syndrome
JAK inhibition may help manage autoimmune conditions in Down syndrome.
research Selenium Compounds and Their Bioactivities: Molecular Mechanisms and Prospects for Functional Food and Therapeutic Applications
Selenium from plants is beneficial and safer for health.