Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
42 citations
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May 2003 in “Mini-reviews in Medicinal Chemistry” New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
3 citations
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March 1994 in “The Journal of Dermatologic Surgery and Oncology” Using a tungsten needle for scalp reduction surgery improves healing, reduces hair loss, and lessens scarring.
September 2017 in “Hair transplant forum international” 49 citations
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December 2007 in “Fertility and Sterility” Stopping finasteride improved sperm counts in two men, reducing the need for fertility treatments.
September 2024 in “Chemico-Biological Interactions” Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.
March 2014 in “Annals of Internal Medicine” Combining α1-blockers with 5α-reductase inhibitors improves urinary symptoms in men.
September 2024 in “Health of Man” Low-dose dutasteride effectively and safely promotes hair growth in men with androgenetic alopecia.
16 citations
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January 2019 in “Pharmaceutical biology” Lespedeza cuneata extract may help treat enlarged prostate.
12 citations
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October 2012 in “International Braz J Urol” Finasteride effectively and safely treats recurrent priapism in children and adolescents with sickle cell disease.
July 2007 in “Journal of Reproduction & Infertility” Short-term finasteride use likely doesn't harm male fertility.
147 citations
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April 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride safely lowers DHT levels without affecting testosterone.
January 2009 in “Journal of Jilin Medical College” SDG helps reduce BPH effects in rats.
May 2008 in “Trends in Urology Gynaecology & Sexual Health” Loop diuretics may double bone loss in elderly men, finasteride lowers prostate cancer risk but may increase high-grade tumors, abarelix reduces testosterone quickly, and transdermal testosterone offers minimal sexual benefit for women.
April 2026 in “The Journal of Urology” Low-dose finasteride may increase erectile dysfunction risk over time.
1 citations
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April 2009 in “Cochrane Database of Systematic Reviews” Finasteride effectively reduces symptoms of male chronic pelvic pain syndrome with few side effects.
20 citations
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April 2012 in “Fertility and Sterility” Finasteride causes lasting fertility decrease in rats.
3 citations
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April 2016 in “Research and reports in urology” The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.
October 2023 in “Bangladesh journal of urology” Finasteride effectively treats hematospermia in 3 months without side effects.
116 citations
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September 2001 in “Journal of The American Academy of Dermatology” Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
July 2013 in “Edinburgh Research Archive (University of Edinburgh)” Dutasteride may reduce insulin sensitivity and increase body fat.
46 citations
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July 2010 in “Advances in Therapy” SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.
September 1999 in “PubMed” Finasteride effectively thickens hair in men with minimal side effects.
8 citations
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February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
15 citations
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July 2016 in “Urologic Clinics of North America” Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
4 citations
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January 1982 in “Endocrinologia Japonica” Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.
August 2010 in “한국한의학연구원 논문집” Phellodendri Cortex Extract may help treat benign prostatic hyperplasia.
October 2023 in “Toxicology and Applied Pharmacology” Finasteride is more harmful to male reproductive health than minoxidil.
2 citations
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July 2006 in “European Urology Supplements” 5α-reductase inhibitors can reduce prostate cancer risk but may increase high-grade tumors, needing more research.