research 5alpha-reductase 2 inhibition impairs brain defeminization of male rats: Reproductive aspects
5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.
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180-210 / 1000+ resultsresearch Nipple Differentiation in Fetal Male Rats Treated with an Inhibitor of the Enzyme 5α-Reductase: Definition of a Selective Role for Dihydrotestosterone*
Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.
research Autophagy protects murine preputial glands against premature aging, and controls their sebum phospholipid and pheromone profile
Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
research Can we predict prostate size by scoring baldness? The relationship of androgenic alopecia and lower urinary tract symptoms
research Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity
Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.
research Platelet-Rich Plasma and Genital Rejuvenation.
Platelet-rich plasma may be effective for genital rejuvenation and deserves more research.
research A cross-sectional observational study showing sebaceous glands differences between psoriatic alopecia and alopecia areata
Sebaceous gland maturity and size differ between psoriatic alopecia and alopecia areata.
research Finasterid in der Behandlung der benignen Prostatahyperplasie
Finasteride effectively reduces prostate size and symptoms in most BPH patients.
research The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration
400 nm particles penetrate hair follicles best, but mouse models aren't fully reliable for human studies.
research Assessment of hair density and caliber in Caucasian and Asian female subjects with female pattern hair loss by using the Folliscope
Caucasian hair is denser, but Asian hair is thicker in female pattern hair loss patients.
research Comparison of Clinical Efficacy of Finasteride and Dutasteride as 5-alpha Reductase Inhibitor
Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.
research QUALITY ASSESSMENT OF HERBAL MEDICINAL PRODUCTS IN BENIGN PROSTATE HYPERTROPHY: CHEMICAL MARKERS AND FINGERPRINT ANALYSIS
Herbal products for benign prostate hypertrophy need better quality checks to ensure safety and effectiveness.
research Second-to-fourth digit ratio and seborrheic dermatitis in males: a cross-sectional study*
Finger length ratios might predict risk for skin condition in males.
research Towards a consensus on how to diagnose and quantify female pattern hair loss – The ‘Female Pattern Hair Loss Severity Index (FPHL-SI)’
New method measures female hair loss: Female Pattern Hair Loss Severity Index (FPHL-SI).
research Is Prenatal Sex Hormone Balance a Risk Factor for the Development of Hidradenitis Suppurativa
Lower 2D:4D finger ratios in HS patients suggest prenatal hormone influence on the disease.
research Effects of Flutamide and Finasteride on Rat Testicular Descent
Androgens, like testosterone, are crucial for early testicular descent in rats.
research Polycystic ovary syndrome is associated with anogenital distance, a marker of prenatal androgen exposure
Women with polycystic ovary syndrome tend to have a longer anogenital distance.
research Development and Validation of a Dermoscopic Severity Score for Female Pattern Hair Loss
A reliable severity score for female pattern hair loss was developed and validated.
research Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: Studies on the natural history of the defect and effect of androgens on gender role
Individuals with this condition often develop male traits and identities at puberty despite being raised as females.
research 5α-reductase inhibitors/finasteride
Finasteride is a safe and effective long-term treatment for prostate enlargement, reducing prostate volume and related symptoms.
research Hair diameter diversity: a clinical sign reflecting the follicle miniaturization.
Different thicknesses of hair strands can indicate the severity of hair thinning.
research The Effects of Perinatal Androgen Deprivation on Sexual Motivation in Male Rats
Blocking androgens at birth reduces sexual motivation in male rats.
research Finasteride as a positive control on reproduction studies
Finasteride causes reproductive malformations in male rats.
research SUN-LB2 Undescended Testicle and Short Stature as Manifestation of Pituitary Stalk Interruption Syndrome a Report From Saudi Arabia
Early diagnosis of PSIS can lead to normal height with growth hormone and testosterone treatment.
research FRI-02 FROM GIRLS TO BOYS TO OLDER MEN, THE INTERESTING TALE OF THE GUEVEDOCES AND 5-ALPHA REDUCTASE INHIBITORS
The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.
research Quantitative study of the human hair follicle in normal scalp and androgenetic alopecia
Alopecia causes smaller hair follicles and affects growth-related structures.
research Association Between Androgenetic Alopecia Severity and Sexual Dysfunction in Male and Female Patients Attending a Dermatology Clinic: An Exploratory Cross-Sectional Study
More severe hair loss is linked to more sexual dysfunction in both men and women.
research Pelvic ultrasound and color Doppler findings in different isosexual precocities
Ultrasound and color Doppler can help diagnose and decide treatment for early puberty in young girls.
research 0885 The androgen-THY1 axis mediates sexual dimorphism in dermal adipogenesis and fibrosis
Androgens reduce THY1 in skin cells, leading to less fat, more fibrosis, and worse healing in males.
research Preputial glands of the albino mouse.
Mouse preputial glands are highly developed sebaceous glands that mainly secrete neutral fat droplets.