research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
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research The Pharma Market as Reflected by Patents
The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Spotlight Commentary: Importance of dose redefining in the process of drug repurposing
Redefining drug dosages is crucial when repurposing them for new uses.
research Farmácia Militar do Laboratório Nacional do Medicamento, Porto e Serviços Farmacêuticos do Centro Hospitalar Universitário do Porto (Hospital de Santo António), EPE, Porto
Pharmacists play a crucial role in patient care and optimizing treatment outcomes.
research Methods for quantifying intrafollicular drug delivery: a critical appraisal
The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.
research Open and Closed Structure
The 3D hair follicle model improves understanding of hair growth and drug testing.
research Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions toward Clinical Reality
A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.
research Understanding the formation mechanism of drug-polymer inclusion complex by structure elucidation and theoretical calculation
The research found how certain drugs and polymers form stable complexes, which could help develop new pharmaceutical forms.
research Targeted skin delivery of topically applied drugs by optimised formulation design
Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.
research Penetration and distribution of three lipophilic probes in vitro in human skin focusing on the hair follicle
Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
research Diffusion properties of model compounds in artificial sebum
Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.
research Can an in vitro hair drug model be developed using dermal papilla cells alone?
Dermal papilla microtissues could be useful for initial hair growth drug testing.
research Formulation development of phospholipid structured carrier systems of methoxsalen and finasteride for skin diseases
research FARMÁCIA ESTÉTICA: NOVAS PERSPECTIVAS DE ATUAÇÃO DO FARMACÊUTICO NA COSMETOLOGIA
Pharmacists play a key role in safe and effective cosmetic use and procedures.
research Triggering of drug release of particles in hair follicles
New method uses hair follicles to deliver drugs deep into the skin.
research Hyperbranched glycerol-based core-amphiphilic branched shell nanotransporters for dermal drug delivery
New nanocarriers improve skin drug delivery with low toxicity at certain concentrations.
research Quantification of nanoparticle uptake into hair follicles in pig ear and human forearm
Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin
The drug was successfully released into hair follicles using nanocarriers.
research Caractérisation physique et chimique des substances à activité thérapeutique : application aux études de profil de stabilité et de préformulation
APIs' stability is influenced by crystalline forms, pressure, and water.
research Peer Review #2 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.
research Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6
LPAR6 has a unique way of binding and activating, which helps in designing treatments for hair loss and cancer.
research Core-shell and core-amphiphilic branched shell nanocarriers based on biodegradable hyperbranched polymers, as potential drug delivery systems
The new biodegradable nanocarriers safely and effectively deliver drugs into the skin.
research Kinetics and Equilibrium of Solute Diffusion into Human Hair
Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.
research Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request
The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.
research Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research Development, validation, and application of an RP-HPLC method for concurrent quantification of Minoxidil and Finasteride in a topical solution for hair regrowth
The document concludes that a new method for measuring Minoxidil and Finasteride in hair regrowth solution is better because it considers separation theory and the properties of the ingredients. The mix of Methanol and water and the pH level greatly impact the measurement time and clarity.
research 5α-Reductase Inhibitors, Chemical and Clinical Models
Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.
![Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds](/images/research/6712367a-949f-47c7-a756-2bfe6316fc69/small/15331.jpg)
research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Nontested Compounds
The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.