research Next-Gen Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
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research Adipose-Derived Stem/Stromal Cells
Fat tissue stem cells show promise for repairing different body tissues and are being tested in clinical trials.
research Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development
Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.
research Possible mechanisms of miniaturization during androgenetic alopecia or pattern hair loss
Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
research Modulation of glucocorticoid action and the treatment of type-2 diabetes
Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
research Effectiveness of Extracellular Vesicle Application in Skin Aging Treatment and Regeneration: Do We Have Enough Evidence from Clinical Trials?
Extracellular vesicles show promise in skin treatments but need more research and standardization.
research The effects of spinach-derived thylakoid supplementation in combination with calorie restriction on anthropometric parameters and metabolic profiles in obese women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled clinical trial
Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.
research No significant impact of platelet‐rich plasma on recovery after Achilles tendon surgery: A double‐blind randomized controlled trial
Platelet-rich plasma does not improve recovery after Achilles tendon surgery.
research Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial
Combining minoxidil with microneedling or spironolactone is more effective for female hair loss than using minoxidil alone.
research Efficacy of spironolactone as adjunctive therapy to sodium valproate in bipolar‐I disorder: A double‐blind, randomized, placebo‐controlled clinical trial
Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.
research Effects of Platelet-Rich Plasma on Hair Growth using Artificial Intelligence-based Trichoscopy and Ki67+ Keratinocytes Analysis: A Randomized Placebo-Controlled Trial
PRP significantly boosts hair growth in androgenic alopecia patients.
research Efficacy of neutral electrolyzed water vs. common topical antiseptics in the healing of full‑thickness burn: Preclinical trial in a mouse model
Superoxidized electrolyzed solution (SES) is more effective for burn healing than common antiseptics.
research Efficacy of the association of topical minoxidil and topical finasteride compared to their use in monotherapy in men with androgenetic alopecia: A prospective, randomized, controlled, assessor blinded, 3‐arm, pilot trial
Using both minoxidil and finasteride together is more effective for hair growth than using either one alone in men with hair loss.
research Lasers in Hair Growth and Hair Transplantation
Lasers are less favored for hair transplant surgery but show promise for hair growth in controlled trials.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer
Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.
research Assessment of the effectiveness and satisfaction of platelet-rich plasma compared with hyaluronic acid in knee osteoarthritis at minimum 7-year follow-up: A post hoc analysis of a randomized controlled trial
Platelet-rich plasma is more effective and satisfactory than hyaluronic acid for knee osteoarthritis.
research A marine protein-based dietary supplement for subclinical hair thinning/loss: Results of a multisite, double-blind, placebo-controlled clinical trial
The supplement helps improve hair growth and reduce hair shedding.
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Comparative efficacy and safety of platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF) and concentrated growth factors (CGF) for female pattern hair loss (FPHL): a prospective multicenter randomized clinical trial
CGF and i-PRF are more effective and safer than PRP for treating female pattern hair loss.
research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial
The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
research Comparative Efficacy of 2% Minoxidil Alone Against Combination of 2% Minoxidil and Low-level Laser therapy in Female Pattern Hair Loss-A Randomized Controlled Trial in Chinese females
Using minoxidil with laser therapy is more effective for female hair loss than minoxidil alone.
research Repurposing of H1-receptor antagonists (levo)cetirizine, (des)loratadine, and fexofenadine as a case study for systematic analysis of trials on clinicaltrials.gov using semi-automated processes with custom-coded software
Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.
research Faculty Opinions recommendation of A randomized, active- and placebo-controlled study of the efficacy and safety of different doses of dutasteride versus placebo and finasteride in the treatment of male subjects with androgenetic alopecia.
Dutasteride 0.5mg was found to be more effective than finasteride 1mg in treating male pattern hair loss, with similar side effects.
research Treatment of alopecia universalis with topical Janus kinase inhibitors – a double blind, placebo, and active controlled pilot study
Topical JAK inhibitors may help treat alopecia universalis by promoting hair regrowth.
research Change in hair growth-related gene expression profile in human isolated hair follicles induced by 5-alpha reductase inhibitors – dutasteride and finasteride – in the presence of testosterone
Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
research Effect of dietary polyunsaturated fatty acids and related nutrients on sebum lipids, and skin and hair coat condition in canines
Diet B improved dogs' skin and hair condition.
research Alopecia Areata: Current Treatments and New Directions
JAK inhibitors and platelet-rich plasma show promise for treating alopecia areata.
research Treatment of hyperandrogenism in polycystic ovary syndrome
Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
research Current understanding and treatment of sex hormone-related hair diseases
Sex hormones affect hair growth and loss, and treatments for related hair diseases include various medications, hair transplantation, and light therapy.