January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
53 citations
,
November 1997 in “Journal of Forensic Sciences” Darker hair in guinea pigs holds more codeine than lighter hair.
10 citations
,
January 2016 in “ACG Case Reports Journal” Long-term Cape Aloe use causes harmless colon pigmentation that can help detect polyps.
14 citations
,
January 2018 in “Skin Appendage Disorders” Upper eyelid hyperpigmentation can help diagnose facial lichen planus pigmentosus in patients with frontal fibrosing alopecia.
4 citations
,
February 2025 in “Pharmaceuticals” Voglibose may help treat skin hyperpigmentation safely.
6 citations
,
January 2018 in “International Journal of Dermatology” Repigmentation patterns in vitiligo depend on melanocyte source, lesion status, and therapy choice.
October 1997 in “Dermatologic Surgery” The Epilight Hair Removal System is effective for temporary hair removal with few side effects, but more research is needed to confirm its safety and long-term results.
March 2007 in “The FASEB Journal” Henna mixed with PPD can cause skin reactions, scarring, and a specific type of baldness, and needs more research to understand these effects.
February 2022 in “Brazilian Journal of Health Review” Most cases were lichen planus pigmentosus, highlighting the need for accurate diagnosis for proper treatment.
21 citations
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January 2019 in “Experimental dermatology” Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
April 2019 in “Journal of Investigative Dermatology” The created skin model with melanoblasts improves the study of skin color and offers an alternative to animal testing.
2 citations
,
July 2009 in “Mayo Clinic Proceedings” A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.
June 2023 in “International Journal of Dermatology” Lichen planus pigmentosus mainly affects middle-aged women with darker skin, is underreported, and is hard to treat.
2 citations
,
November 1995 in “American Journal of Obstetrics and Gynecology” Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.
10 citations
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July 2022 in “Journal of Cosmetic Dermatology” Medicago sativa extract may help treat vitiligo by enhancing skin and hair pigmentation.
7 citations
,
August 2013 in “Experimental and Therapeutic Medicine” 1,25-dihydroxyvitamin D3 helps melanocyte precursors from hair follicles grow and produce melanin, aiding vitiligo treatment understanding.
April 2024 in “Authorea (Authorea)” Stopping heptaminol medication reversed hair color loss in a patient on dialysis.
July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
September 2022 in “Pharmacy Today” 11 citations
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March 2012 in “Journal of the American Academy of Dermatology” Most patients with dark skin were satisfied with laser hair removal and had few complications.
January 2026 in “Frontiers in Medicine” PP-PTKL may help treat hair greying, but more testing is needed.
November 2024 in “Rheumatology Advances in Practice” Monitor for early signs of azathioprine toxicity and check blood counts regularly.
December 2024 in “Journal of Clinical Medicine of Kazakhstan” Vitiligo treatments include JAK inhibitors, UVB phototherapy, and dietary changes, with emotional support being important.
5 citations
,
August 2014 in “Dermatologic surgery” Advanced fluorescence technology effectively treats skin discoloration from certain creams.
The document concludes that dermatology training and grading scales need to better represent dark-skinned individuals to improve diagnosis and assessment of skin conditions.
16 citations
,
February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
April 2026 in “The FASEB Journal” Exosomal miR-199a-3p from dermal papilla cells helps control hair color by affecting melanocytes.
February 2009 in “Journal of The American Academy of Dermatology” Pulsed dye laser treatment was effective for a skin condition resistant to other treatments.
4 citations
,
January 2024 in “Allergy” Everyone has an immune response to PPD, but reactions differ, causing tolerance, mild inflammation, or allergy.
2 citations
,
January 2019 in “Springer eBooks” Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.